Changes in CREB (SER133) Content and DNA-Binding Activity of Transcriptional Factors in Rat Brain Cells against the Background of Ladasten Exposure

被引：0

作者：

Salimgareeva, M. Kh. ^{[1
]}

Vakhitova, Yu. V. ^{[1
]}

Yamidanov, R. S. ^{[1
]}

Sadovnikov, S. V. ^{[1
]}

Seredenin, S. B. ^{[2
]}

机构：

[1] Russian Acad Sci, Lab Mol Immunol & Pharmacol, Inst Biochem & Genet, Ufa Res Ctr, Moscow, Russia

[2] Russian Acad Med Sci, Inst Pharmacol, Moscow 109801, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2009年 / 147卷 / 05期

关键词：

ladasten; hypothalamus; hippocampus; striatum; transcriptional factors; MICE;

D O I：

10.1007/s10517-009-0573-4

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We studied the effects of single administration of ladasten (50 mg/kg) on the level of transcriptional factor CREB (cyclic AMP response binding element protein) phosphorylated by Ser133 in rat striatum, hypothalamus, and hippocampus. Transcriptional factors with affected DNA-binding activity were identified in brain cells.

引用

页码：599 / 602

页数：4

共 4 条

[1] Changes in CREB (SER133) Content and DNA-Binding Activity of Transcriptional Factors in Rat Brain Cells against the Background of Ladasten Exposure
M. Kh. Salimgareeva
Yu. V. Vakhitova
R. S. Yamidanov
S. V. Sadovnikov
S. B. Seredenin
Bulletin of Experimental Biology and Medicine, 2009, 147 : 599 - 602
[2] AGE-RELATED-CHANGES IN DNA-BINDING ACTIVITY OF TRANSCRIPTION FACTORS IN RAT-BRAIN
ASANUMA, M
OGAWA, N
NISHIBAYASHI, S
IWATA, E
KONDO, Y
MORI, A
JOURNAL OF NEUROCHEMISTRY, 1995, 65 : S98 - S98
[3] Chronic citalopram treatment induces time-dependent changes in the expression and DNA-binding activity of transcription factor AP-2 in rat brain
Berggård, C
Damberg, M
Oreland, L
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2003, 13 (01) : 11 - 17
[4] DYNAMIC CHANGES IN THE COMPOSITION OF THE AP-1 TRANSCRIPTION FACTOR DNA-BINDING ACTIVITY IN RAT-BRAIN FOLLOWING KAINATE-INDUCED SEIZURES AND CELL-DEATH
KAMINSKA, B
FILIPKOWSKI, RK
ZURKOWSKA, G
LASON, W
PRZEWLOCKI, R
KACZMAREK, L
EUROPEAN JOURNAL OF NEUROSCIENCE, 1994, 6 (10) : 1558 - 1566

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