Eosinophilic esophagitis

Eosinophilic esophagitis is a major cause of dysphagia and esophageal food impaction in young adults, although the diagnostic can be made in older patients. The diagnosis of eosinophilic esophagitis is suspected on endoscopic abnormalities of esophageal mucosa and confirmed by esophageal biopsy samples. Approximately 50% of patients with eosinophilic esophagitis do respond to proton pump inhibitors therapy. The first line therapy for eosinophilic esophagitis is proton pump inhibitor therapy. Ingested topical steroids represent a second-line therapy. The practical modalities of this treatment should be clearly explained to patients. A diet that eliminates most alimentary allergens provide a 75% clinical and histological remission rate. The progressive reintroduction protocol allows to identify the allergen(s) involved in the disease. Endoscopic dilatations should be proposed in patients with significant esophageal stricture.