Wake-sleep circuitry: an overview

被引：225
|
作者：
Saper, Clifford B. [1 ]
Fuller, Patrick M.
机构：
[1] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Neurol, Program Neurosci, Boston, MA 02215 USA
来源：
CURRENT OPINION IN NEUROBIOLOGY | 2017年 / 44卷
关键词：
PEDUNCULOPONTINE TEGMENTAL NUCLEUS; BASAL FOREBRAIN NEURONS; PARADOXICAL REM SLEEP; GABAERGIC NEURONS; FEEDFORWARD INHIBITION; LATERAL HYPOTHALAMUS; CHOLINERGIC NEURONS; DISCHARGE PROFILES; PARABRACHIAL AREA; PREOPTIC NUCLEUS;
D O I：
10.1016/j.conb.2017.03.021
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Although earlier models of brain circuitry controlling wake sleep focused on monaminergic and cholinergic arousal systems, recent evidence indicates that these play mainly a modulatory role, and that the backbone of the wake sleep regulatory system depends upon fast neurotransmitters, such as glutmate and GABA. We review here recent advances in understanding the role these systems play in controlling sleep and wakefulness.
引用
收藏
页码：186 / 192
页数：7
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