Loss of function mutations of PI3Kγ or PLCβ2/β3 impair T-cell migration to SDF.

被引：0
|
作者：
Bach, TL
Huang, MZ
Wu, DQ
Zigmond, SH
Abrams, CS
机构：
[1] Univ Penn, Sch Med, Philadelphia, PA 19104 USA
[2] Univ Connecticut, Ctr Hlth, Farmington, CT USA
来源：
BLOOD | 2002年 / 100卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
2633
引用
收藏
页码：669A / 669A
页数：1
相关论文
共 50 条
  • [1] Roles of PLC-β2, -β3, and PI3K in T-cell migration to SDF 1-α.
    Bach, TL
    Chen, QM
    Jordan, MS
    Wu, DQ
    Zigmond, SH
    Abrams, CS
    BLOOD, 2003, 102 (11) : 768A - 768A
  • [2] Function of PI3Kγ in thymocyte development, T cell activation, and neutrophil migration
    Sasaki, T
    Irie-Sasaki, J
    Jones, RG
    Oliveira-dos-Santos, AJ
    Stanford, WL
    Bolon, B
    Wakeham, A
    Itie, A
    Bouchard, D
    Kozieradzki, I
    Joza, N
    Mak, TW
    Ohashi, PS
    Suzuki, A
    Penninger, JM
    SCIENCE, 2000, 287 (5455) : 1040 - 1046
  • [3] Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ
    Mayuko Uehara
    Martina M. McGrath
    Shunsuke Ohori
    Zhabiz Solhjou
    Naima Banouni
    Sujit Routray
    Catherine Evans
    Jonathan P. DiNitto
    Abdallah Elkhal
    Laurence A. Turka
    Terry B. Strom
    Stefan G. Tullius
    David G. Winkler
    Jamil Azzi
    Reza Abdi
    Nature Communications, 8
  • [4] Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ
    Uehara, Mayuko
    McGrath, Martina M.
    Ohori, Shunsuke
    Solhjou, Zhabiz
    Banouni, Naima
    Routray, Sujit
    Evans, Catherine
    DiNitto, Jonathan P.
    Elkhal, Abdallah
    Turka, Laurence A.
    Strom, Terry B.
    Tullius, Stefan G.
    Winkler, David G.
    Azzi, Jamil
    Abdi, Reza
    NATURE COMMUNICATIONS, 2017, 8
  • [5] Inactivation of PI3Kγ and PI3Kδ distorts T-cell development and causes multiple organ inflammation
    Ji, Hong
    Rintelen, Felix
    Waltzinger, Caroline
    Meier, Dominique Bertschy
    Bilancio, Antonio
    Pearce, Wayne
    Hirsch, Emilio
    Wymann, Matthias P.
    Rueckle, Thomas
    Camps, Montserrat
    Vanhaesebroeck, Bart
    Okkenhaug, Klaus
    Rommel, Christian
    BLOOD, 2007, 110 (08) : 2940 - 2947
  • [6] The PI3K/AKT signaling pathway in regulatory T-cell development, stability, and function
    Pompura, Saige L.
    Dominguez-Villar, Margarita
    JOURNAL OF LEUKOCYTE BIOLOGY, 2018, 103 (06) : 1065 - 1076
  • [7] A requirement for PI3K in gamma delta T-cell development
    Sumaria, N.
    Grandjean, C. L. A.
    Pang, D. J.
    Neves, J. F.
    Stoenchev, K. V.
    Silva-Santos, B.
    Pennington, D. J.
    IMMUNOLOGY, 2014, 143 : 53 - 53
  • [8] Evaluation of the PI3K pathway in peripheral t-cell lymphoma
    Lim, S. T.
    Nairismagi, M-L.
    Tan, S. H.
    Thit, E. E.
    Politz, O.
    Liu, N.
    Ong, C. K.
    ANNALS OF ONCOLOGY, 2017, 28
  • [9] PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization
    Bach, Tami L.
    Kerr, Wesley T.
    Wang, Yanfeng
    Bauman, Eve Marie
    Kine, Purnima
    Whiteman, Eileen L.
    Morgan, Renell S.
    Williamson, Edward K.
    Ostap, E. Michael
    Burkhardt, Janis K.
    Koretzky, Gary A.
    Birnbaum, Morris J.
    Abrams, Charles S.
    BLOOD, 2007, 109 (03) : 1147 - 1155
  • [10] Roles of PI3Kγ and PI3Kδ in mantle cell lymphoma proliferation and migration contributing to efficacy of the PI3Kγ/δ inhibitor duvelisib
    Till, Kathleen J.
    Abdullah, Mariah
    Alnassfan, Tahera
    Janet, Gallardo Zapata
    Marks, Thomas
    Coma, Silvia
    Weaver, David T.
    Pachter, Jonathan A.
    Pettitt, Andrew R.
    Slupsky, Joseph R.
    SCIENTIFIC REPORTS, 2023, 13 (01)
12345