New intragastric sleeve technique reduces adipose tissue in pig experimental model: tomographic study

被引:1
|
作者
Ribeiro, Mariana da Silva [1 ]
Araujo dos Scheiba Zorron, Ricardo Paiva [2 ]
Quina Silva, Saulo Jose [1 ]
Ruiz Cadena, Silvia Marcela [1 ]
dos Santos Junior, Marcelo Borges [1 ]
Antunes, Fernanda [1 ]
Vieira, Guilherme de Souza [1 ]
Quirino, Celia Raquel [3 ]
de Abreu Oliveira, Andre Lacerda [1 ]
机构
[1] State Univ Northern Rio de Janeiro, Lab Anim Med & Surg, Campos Dos Goytacazes, RJ, Brazil
[2] Klinikum Bremerhaven Reinkenheide, Div Innovat Surg, Dept Surg, Postbrookstr 103, D-27574 Bremerhaven, Germany
[3] State Univ Northern Rio de Janeiro, Lab Anim Reprod & Genet Improvement, Campos Dos Goytacazes, RJ, Brazil
关键词
D O I
10.1038/s41598-020-74846-8
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
In order to implement a new bariatric surgery technique, we verify the efficacy of intragastric sleeve to reduce weight gain and subcutaneous adipose tissue (SAT). Animals were divided into two groups: G1 (single-port intragastric sleeve) and G2 (sham group). The stomach was surgically reduced by single-port intragastric sutures to fo a gastric sleeve. Animals were submitted to computer tomography (CT) before the surgical procedure and after 18 weeks. Images were analyzed and measurements of the thickness of SAT, depth and width of the longissimus dorsi muscle and the rib eye area were made. Body weight and CT measurements were analyzed using the GLM PROC. The correlation coefficients were calculated among weight, moments and measures. There was a significant difference in weight gain, in which G1 had an average of 42.803 +/- 3.206 kg, lower than G2 (45.966 +/- 4.767 kg). The mean values for SAT and muscle measurements differed significantly between groups, in which G1 achieved the lowest values. All variables had significant correlations and high magnitude. Intragastric sleeve surgery induced a significant decrease of SAT. The new intragastric sleeve technique is feasible, safe and effective, mainly in reducing fat deposition, making it an important alternative in bariatric surgical treatment.
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页数:8
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