Overexpression of GTP-Cyclohydrolase I in Vascular Endothelium Prevents Oxidative Stress-Induced eNOS Translocation From Caveolae to Cytosol

被引:0
|
作者
Peterson, Timothy E. [1 ]
Katusic, Zvonimir S. [1 ]
d'Usclo, Livius V. [1 ]
机构
[1] Mayo Clin, Rochester, MN USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:S1011 / S1011
页数:1
相关论文
共 50 条
  • [1] Telmisartan treatment upregulates GTP-cyclohydrolase I and prevents eNOS uncoupling in streptozotocin-induced diabetes
    Daiber, Andreas
    Oelze, Matthias
    Wenzel, Philip
    Mueller, Johanna
    Alhamdani, Mohamed S. S.
    Reifenberg, Kurt
    Muenzel, Thomas
    FASEB JOURNAL, 2008, 22
  • [2] Small Mesenteric Arteries Are Resistant to Oxidative Stress Induced by eNOS Uncoupling in GTP-Cyclohydrolase I-Deficient Mice
    d'Uscio, Livius V.
    Katusic, Zvonimir S.
    CIRCULATION, 2011, 124 (21)
  • [3] GTP-cyclohydrolase I increases by aging to suppress the oxidative stress induced human nonmelanoma skin cancer
    Nakai, K.
    Yoneda, K.
    Moriue, T.
    Kubota, Y.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2016, 136 (05) : S53 - S53
  • [4] Endothelium-targeted transgenic GTP-cyclohydrolase I overexpression inhibits neointima formation in mouse carotid artery
    Liao, Song-Jie
    Lin, Li
    Zeng, Jin-Sheng
    Huang, Ru-Xun
    Channon, Keith M.
    Chen, Alex F.
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2007, 34 (12) : 1260 - 1266
  • [5] Endothelium-specific GTP cyclohydrolase I overexpression accelerates refractory wound healing by suppressing oxidative stress in diabetes
    Tie, Lu
    Li, Xue-Jun
    Wang, Xian
    Channon, Keith M.
    Chen, Alex F.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2009, 296 (06): : E1423 - E1429
  • [6] Atorvastatin treatment reduces vascular oxidative stress and improves endothelial dysfunction in streptozotocin-induced diabetes mellitus by increasing the expression of GTP-cyclohydrolase I
    Wenzel, Philip
    Oelze, Matthias
    Thum, Thomas
    Steinhoff, Lena
    Brandt, Moritz
    Daiber, Andreas
    Muenzel, Thomas
    CIRCULATION, 2006, 114 (18) : 329 - 330
  • [7] Atorvastatin rapidly improves eNOS coupling in human internal mammary arteries, by stimulating GTP-cyclohydrolase I expression and improving vascular tetrahydrobiopterin bioavailability
    Bakogiannis, C.
    Antoniades, C.
    Tousoulis, D.
    Hale, A.
    Demosthenous, M.
    Antonopoulos, A. S.
    Economopoulos, G.
    Psarros, C.
    Stefanadis, C.
    Channon, K. M.
    EUROPEAN HEART JOURNAL, 2011, 32 : 156 - 156
  • [8] Lithium prevents stress-induced reduction of vascular endothelium growth factor levels
    Silva, Rui
    Martins, Luis
    Longatto-Filho, Adhemar
    Almeida, Osborne F. X.
    Sousa, Nuno
    NEUROSCIENCE LETTERS, 2007, 429 (01) : 33 - 38
  • [9] Induction of Vascular GTP-Cyclohydrolase I and Endogenous Tetrahydrobiopterin Synthesis Protect Against Inflammation-Induced Endothelial Dysfunction in Human Atherosclerosis
    Antoniades, Charalambos
    Cunnington, Colin
    Antonopoulos, Alexis
    Neville, Matt
    Margaritis, Marios
    Demosthenous, Michael
    Bendall, Jennifer
    Hale, Ashley
    Cerrato, Ruha
    Tousoulis, Dimitris
    Bakogiannis, Constantinos
    Marinou, Kyriakoula
    Toutouza, Marina
    Vlachopoulos, Charalambos
    Leeson, Paul
    Stefanadis, Christodoulos
    Karpe, Fredrik
    Channon, Keith M.
    CIRCULATION, 2011, 124 (17) : 1860 - 1870
  • [10] Endothelium-targeted GTP cyclohydrolase I overexpression inhibits wire injury-induced restenosis in mouse carotid artery
    Lin, L
    Liao, SJ
    Fink, GD
    Chen, AF
    HYPERTENSION, 2005, 46 (04) : 826 - 827