Structural Changes in the Acceptor Site of Photosystem II upon Ca2+/Sr2+ Exchange in the Mn4CaO5 Cluster Site and the Possible Long-Range Interactions

被引：5
|
作者：
Koua, Faisal Hammad Mekky [1 ,2 ]
机构：
[1] Deutsch Elektronen Synchrotron DESY, Ctr Free Electron Laser Sci, Notkestr 85, D-22607 Hamburg, Germany
[2] Natl Univ Sudan, Natl Univ Biomed Res Inst, Air St,POB 3783, Khartoum 11111, Sudan
来源：
BIOMOLECULES | 2019年 / 9卷 / 08期
基金：
欧洲研究理事会;
关键词：
photosystem II; redox potential; electron transfer; charge separation; photoinhibition; water oxidation; RHODOBACTER-SPHAEROIDES; THERMOSYNECHOCOCCUS-ELONGATUS; PROTEIN-STRUCTURE; ELECTRON-TRANSFER; REDOX POTENTIALS; BINDING; Q(A); RESOLUTION; MECHANISM; SPECTROSCOPY;
D O I：
10.3390/biom9080371
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The Mn4CaO5 cluster site in the oxygen-evolving complex (OEC) of photosystem II (PSII) undergoes structural perturbations, such as those induced by Ca2+/Sr2+ exchanges or Ca/Mn removal. These changes have been known to induce long-range positive shifts (between +30 and +150 mV) in the redox potential of the primary quinone electron acceptor plastoquinone A (Q(A)), which is located 40 angstrom from the OEC. To further investigate these effects, we reanalyzed the crystal structure of Sr-PSII resolved at 2.1 angstrom and compared it with the native Ca-PSII resolved at 1.9 angstrom. Here, we focus on the acceptor site and report the possible long-range interactions between the donor, Mn4Ca(Sr)O-5 cluster, and acceptor sites.
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页数：8
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