DICER PREVENTS HYPOXIA-INDUCED UP-REGULATION OF HIF-1A, HYPOXIC RESPONSE AND EPITHELIAL-MESENCHYMAL TRANSITION IN HEPATOCELLULAR CARCINOMA

被引：0
|
作者：
Ibrahim, A. A. [1 ]
Schmithals, C. [1 ]
Kowarz, E. [2 ]
Koeberle, V. [1 ]
Kakoschky, B. [1 ]
Pleli, T. [1 ]
Waidmann, O. [1 ]
Finkelmeier, F. [1 ]
Zeuzem, S. [1 ]
Korf, H. W. [3 ]
Kronenberger, B. [1 ]
Marschalek, R. [2 ]
Piiper, A. [1 ]
机构：
[1] Univ Hosp Frankfurt, Dept Med 1, Frankfurt, Germany
[2] Goethe Univ Frankfurt, Inst Pharmaceut Biol, Bioctr, Frankfurt, Germany
[3] Univ Hosp Frankfurt, Inst Anat 2, Frankfurt, Germany
来源：
JOURNAL OF HEPATOLOGY | 2016年 / 64卷
关键词：
D O I：
10.1016/S0168-8278(16)00997-1
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
FRI-026
引用
收藏
页码：S555 / S555
页数：1
相关论文
共 50 条
  • [1] Hypoxia-Induced Epithelial-Mesenchymal Transition in Cancers: HIF-1α and Beyond
    Tam, Shing Yau
    Wu, Vincent W. C.
    Law, Helen K. W.
    [J]. FRONTIERS IN ONCOLOGY, 2020, 10
  • [2] Wnt/β-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling
    Zhang, Qi
    Bai, Xueli
    Chen, Wei
    Ma, Tao
    Hu, Qida
    Liang, Chao
    Xie, Shangzhi
    Chen, Conglin
    Hu, Liqiang
    Xu, Shiguo
    Liang, Tingbo
    [J]. CARCINOGENESIS, 2013, 34 (05) : 962 - 973
  • [3] HIF-1α mediates Hypoxia-induced epithelial-mesenchymal transition in peritoneal mesothelial cells
    Morishita, Yoshiyuki
    Ookawara, Susumu
    Hirahara, Ichiro
    Muto, Shigeaki
    Nagata, Daisuke
    [J]. RENAL FAILURE, 2016, 38 (02) : 282 - 289
  • [4] Basil polysaccharide inhibits hypoxia-induced hepatocellular carcinoma metastasis and progression through suppression of HIF-1α-mediated epithelial-mesenchymal transition
    Feng, Bing
    Zhu, Ying
    Sun, Chaoyue
    Su, Zuqing
    Tang, Lipeng
    Li, Caiyun
    Zheng, Guangjuan
    [J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 137 : 32 - 44
  • [5] DEC1 promotes hypoxia-induced epithelial-mesenchymal transition (EMT) in human hepatocellular carcinoma cells
    Murakami, Keishu
    Wu, Yunyan
    Imaizumi, Tadaatsu
    Aoki, Yuka
    Liu, Qiang
    Yan, Xu
    Seino, Hiroko
    Yoshizawa, Tadashi
    Morohashi, Satoko
    Kato, Yukio
    Kijima, Hiroshi
    [J]. BIOMEDICAL RESEARCH-TOKYO, 2017, 38 (04): : 221 - 227
  • [6] Hyperthermia inhibits hypoxia-induced epithelial-mesenchymal transition in HepG2 hepatocellular carcinoma cells
    Yuan, Guang-Jin
    Li, Qian-Wen
    Shan, Shun-Lin
    Wang, Wu-Ming
    Jiang, Sen
    Xu, Xi-Ming
    [J]. WORLD JOURNAL OF GASTROENTEROLOGY, 2012, 18 (34) : 4781 - 4786
  • [7] Hyperthermia inhibits hypoxia-induced epithelial-mesenchymal transition in HepG2 hepatocellular carcinoma cells
    Guang-Jin Yuan
    [J]. World Journal of Gastroenterology, 2012, (34) : 4781 - 4786
  • [8] Activation of PI3 kinase/Akt/HIF-1α pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma
    Jiao, Min
    Nan, Ke-Jun
    [J]. INTERNATIONAL JOURNAL OF ONCOLOGY, 2012, 40 (02) : 461 - 468
  • [9] Downregulation of AIF by HIF-1 contributes to hypoxia-induced epithelial-mesenchymal transition of colon cancer
    Xiong, Zhong
    Guo, Meng
    Yu, Yun
    Zhang, Fei-Fei
    Ge, Meng-Kai
    Chen, Guo-Qiang
    Shen, Shao-Ming
    [J]. CARCINOGENESIS, 2016, 37 (11) : 1079 - 1088
  • [10] Paeoniflorin prevents hypoxia-induced epithelial-mesenchymal transition in human breast cancer cells
    Zhou, Zhenyu
    Wang, Shunchang
    Song, Caijuan
    Hu, Zhuang
    [J]. ONCOTARGETS AND THERAPY, 2016, 9 : 2511 - 2518
12345