Medial Temporal Lobe High Resolution Magnetic Resonance Images for the Early Diagnosis of Alzheimer's Disease

被引：1
|
作者：
Brun, Francesco [1 ,2 ]
Sensi, Francesco [3 ,4 ]
Quartulli, Rossella [2 ]
Rei, Luca [3 ]
Grucka, Alban [1 ]
Mancarella, Valentina [1 ,5 ]
Chincarini, Andrea [3 ]
Ukmar, Maja [6 ]
Accardo, Agostino [1 ]
Longo, Renata [2 ,7 ]
机构：
[1] Univ Trieste, Dipartimento Ingn & Architettura, Via A Valerio 10, I-34127 Trieste, Italy
[2] Ist Nazl Fis Nucl, Sez Trieste, I-34127 Trieste, Italy
[3] Ist Nazl Fis Nucl, Sez Genova, I-16146 Genoa, Italy
[4] Univ Genoa, Dipartimento Fis, I-16146 Genoa, Italy
[5] Fdn IRCCS Ist Nazl Tumori, I-20133 Milan, Italy
[6] Azienda Osped Univ Osped Riuniti Trieste, Unita Clin Operat Radiol, I-34142 Trieste, Italy
[7] Univ Trieste, Dipartimento Fis, I-34127 Trieste, Italy
来源：
2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) | 2015年
关键词：
MILD COGNITIVE IMPAIRMENT;
D O I：
10.1109/EMBC.2015.7319339
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
A challenging point in neuroimaging is the diagnosis of Alzheimer's disease (AD) during its asymptomatic phase. Among all the biomarkers proposed in the literature, a measure of the hippocampal atrophy via Magnetic Resonance Imaging (MRI) seems to be one of the most reliable. Refined image processing techniques were already proposed to automatically extract the hippocampal boxes from images acquired with the standard full brain acquisition protocol suggested by the Alzheimer's Disease Neuroimaging Initiative (ADNI). In order to enhance this approach, here we propose a high resolution (HR) MRI protocol focused on the medial temporal lobe (MTL) mainly conceived for 1.5T MRI device, hereafter referred as MTL-HR protocol. A preliminary characterization of its behavior when compared to the standard ADNI protocol is also presented.
引用
收藏
页码：4274 / 4277
页数：4
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