Knockout of P2Y12 aggravates experimental autoimmune encephalomyelitis in mice via increasing of IL-23 production and Th17 cell differentiation by dendritic cells (vol 62, pg 245, 2017)

被引:0
|
作者
Zhang, Jiang [1 ]
Li, Zhenlong [1 ]
Hu, Xuefei [1 ]
Su, Qiong [1 ]
He, Cong [1 ]
Liu, Jing [1 ]
Ren, Hua [1 ]
Qian, Min [1 ]
Liu, Junling [3 ]
Cui, Shufang [2 ]
Jiang, Wenzheng [1 ]
机构
[1] East China Normal Univ, Shanghai Key Lab Regulatory Biol, Sch Life Sci, Shanghai, Peoples R China
[2] Second Mil Med Univ, Lab Anim Ctr, Shanghai, Peoples R China
[3] Shanghai Jiao Tong Univ, Dept Biochem & Mol Cell Biol, Sch Med, Shanghai, Peoples R China
关键词
D O I
10.1016/j.bbi.2020.09.020
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页数:3
相关论文
共 12 条
  • [1] Knockout of P2Y12 aggravates experimental autoimmune encephalomyelitis in mice via increasing of IL-23 production and Th17 cell differentiation by dendritic cells
    Zhang, Jiang
    Li, Zhenlong
    Hu, Xuefei
    Su, Qiong
    He, Cong
    Liu, Jing
    Ren, Hua
    Qian, Min
    Liu, Junling
    Cui, Shufang
    Jiang, Wenzheng
    BRAIN BEHAVIOR AND IMMUNITY, 2017, 62 : 245 - 255
  • [2] Critical Role of P2Y12 Receptor in Regulation of Th17 Differentiation and Experimental Autoimmune Encephalomyelitis Pathogenesis
    Qin, Chaoyan
    Zhou, Jinfeng
    Gao, Yuan
    Lai, Weiming
    Yang, Cuixia
    Cai, Yingying
    Chen, Shuai
    Du, Changsheng
    JOURNAL OF IMMUNOLOGY, 2017, 199 (01): : 72 - 81
  • [3] P2Y6 Deficiency Enhances Dendritic Cell-Mediated Th1/Th17 Differentiation and Aggravates Experimental Autoimmune Encephalomyelitis
    Li, Zhenlong
    He, Cong
    Zhang, Jiang
    Zhang, Hongmei
    Wei, Huan
    Wu, Shijia
    Jiang, Wenzheng
    JOURNAL OF IMMUNOLOGY, 2020, 205 (02): : 387 - 397
  • [4] Betaine Ameliorates Experimental Autoimmune Encephalomyelitis by Inhibiting Dendritic Cell-Derived IL-6 Production and Th17 Differentiation
    Yang, Cuixia
    Lai, Weiming
    Zhou, Jinfeng
    Zheng, Xinyuan
    Cai, Yingying
    Yang, Wanjie
    Xie, Sirong
    Gao, Yuan
    Du, Changsheng
    JOURNAL OF IMMUNOLOGY, 2018, 200 (04): : 1316 - 1324
  • [5] Betaine ameliorates experimental autoimmune encephalomyelitis by inhibiting dendritic cell-derived IL-6 production and Th17 differentiation
    Yang, C.
    Yu, X.
    Xing, J.
    Gong, R.
    Zhou, Q.
    Xiang, Z.
    Lv, J.
    Du, C.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 986 - 986
  • [6] Dendritic cell differentiation in the presence of PGE2 primes dendritic cells for a proinflammatory response, induces IL-23, and promotes Th17 differentiation
    Khayrullina, Tanzilya R.
    Yen, Jui-Hung
    Ganea, Doina
    FASEB JOURNAL, 2008, 22
  • [7] In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells
    Khayrullina, Tanzilya
    Yen, Jui-Hung
    Jing, Huie
    Ganea, Doina
    JOURNAL OF IMMUNOLOGY, 2008, 181 (01): : 721 - 735
  • [8] Blocking A2B Adenosine Receptor Alleviates Pathogenesis of Experimental Autoimmune Encephalomyelitis via Inhibition of IL-6 Production and Th17 Differentiation
    Wei, Wei
    Du, Changsheng
    Lv, Jie
    Zhao, Guixian
    Li, Zhenxin
    Wu, Zhiying
    Hasko, Gyoergy
    Xie, Xin
    JOURNAL OF IMMUNOLOGY, 2013, 190 (01): : 138 - 146
  • [9] Expression of Tyk2 in dendritic cells is required for IL-12, IL-23, and IFN-γ production and the induction of Th1 cell differentiation
    Tokumasa, Naoki
    Suto, Akira
    Kagarni, Shin-ichiro
    Furuta, Shunsuke
    Hirose, Koichi
    Watanabe, Norihiko
    Saito, Yasushi
    Shimoda, Kazuya
    Iwamoto, Itsuo
    Nakajima, Hiroshi
    BLOOD, 2007, 110 (02) : 553 - 560
  • [10] Enhanced T cell proliferation, Th17 differentiation and unaltered IL-10 production lead to marginally enhanced development of experimental autoimmune encephalomyelitis in EBI3-deficient mice
    Bai, Xue-Feng
    Liu, Jin-Qing
    Carl, Joseph, Jr.
    Liu, Zhenzhen
    Zhang, Xuejun
    Talebian, Fatemeh
    Shi, Fu-Dong
    Whitacre, Caroline
    Trgovcich, Joanne
    JOURNAL OF IMMUNOLOGY, 2011, 186