Guidelines for Management of Idiopathic Normal Pressure Hydrocephalus (Third Edition): Endorsed by the Japanese Society of Normal Pressure Hydrocephalus

被引：190

作者：

Nakajima, Madoka ^{[1
]}

Yamada, Shigeki ^{[2
]}

Miyajima, Masakazu ^{[3
]}

Ishii, Kazunari ^{[4
]}

Kuriyama, Nagato ^{[5
]}

Kazui, Hiroaki ^{[6
]}

Kanemoto, Hideki ^{[7
]}

Suehiro, Takashi ^{[7
]}

Yoshiyama, Kenji ^{[7
]}

Kameda, Masahiro ^{[8
]}

Kajimoto, Yoshinaga ^{[9
]}

Mase, Mitsuhito ^{[10
]}

Murai, Hisayuki ^{[11
]}

Kita, Daisuke ^{[12
]}

Kimura, Teruo ^{[13
]}

Samejima, Naoyuki ^{[14
]}

Tokuda, Takahiko ^{[15
]}

Kaijima, Mitsunobu ^{[16
]}

Akiba, Chihiro ^{[3
]}

Kawamura, Kaito ^{[1
]}

Atsuchi, Masamichi ^{[17
]}

Hirata, Yoshihumi ^{[18
]}

Matsumae, Mitsunori ^{[19
]}

Sasaki, Makoto ^{[20
]}

Yamashita, Fumio ^{[20
]}

Aoki, Shigeki ^{[21
]}

Irie, Ryusuke ^{[21
]}

Miyake, Hiroji ^{[22
]}

Kato, Takeo ^{[23
]}

Mori, Etsuro ^{[24
]}

Ishikawa, Masatsune ^{[25
,26
]}

Date, Isao ^{[8
]}

Arai, Hajime ^{[1
]}

机构：

[1] Juntendo Univ, Dept Neurosurg, Fac Med, Tokyo, Japan

[2] Shiga Univ Med Sci, Dept Neurosurg, Otsu, Shiga, Japan

[3] Juntendo Tokyo Koto Geriatr Med Ctr, Dept Neurosurg, Tokyo, Japan

[4] Kindai Univ, Dept Radiol, Fac Med, Osakasayama, Osaka, Japan

[5] Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Epidemiol Community Hlth & Med, Kyoto, Japan

[6] Kochi Univ, Kochi Med Sch, Dept Neuropsychiat, Kochi, Japan

[7] Osaka Univ, Dept Psychiat, Grad Sch Med, Suita, Osaka, Japan

[8] Okayama Univ, Dept Neurol Surg, Grad Sch Med Dent & Pharmaceut Sci, Okayama, Okayama, Japan

[9] Osaka Med Coll, Dept Neurosurg, Div Surg, Takatsuki, Osaka, Japan

[10] Nagoya City Univ, Grad Sch Med Sci, Dept Neurosurg, Nagoya, Aichi, Japan

[11] Chibaken Saiseikai Narashino Hosp, Dept Neurosurg, Narashino, Chiba, Japan

[12] Noto Gen Hosp, Dept Neurosurg, Nanao, Ishikawa, Japan

[13] Kitami Red Cross Hosp, Dept Neurosurg, Kitami, Hokkaido, Japan

[14] Tokyo Kyosai Hosp, Dept Neurosurg, Federat Natl Publ Serv Personnel Mutual Aid Assoc, Tokyo, Japan

[15] Natl Inst Quantum & Radiol Sci & Technol, Natl Inst Radiol Sci, Dept Funct Brain Imaging Res, Chiba, Chiba, Japan

[16] Hokushinkai Megumino Hosp, Dept Neurosurg, Eniwa, Hokkaido, Japan

[17] Jifukai Atsuchi Neurosurg Hosp, Normal Pressure Hydrocephalus Ctr, Kagoshima, Kagoshima, Japan

[18] Kumamoto Takumadai Hosp, Dept Neurosurg, Kumamoto, Kumamoto, Japan

[19] Tokai Univ, Sch Med, Dept Neurosurg, Isehara, Kanagawa, Japan

[20] Iwate Med Univ, Inst Biomed Sci, Div Ultrahigh Field MRI, Yahaba, Iwate, Japan

[21] Juntendo Univ, Dept Radiol, Sch Med, Tokyo, Japan

[22] Nishinomiya Kyoritsu Rehabil Hosp, Nishinomiya, Hyogo, Japan

[23] Yamagata Univ, Dept Internal Med 3, Div Neurol & Clin Neurosci, Sch Med, Yamagata, Yamagata, Japan

[24] Osaka Univ, Dept Behav Neurol & Neuropsychiat, United Grad Sch Child Dev, Suita, Osaka, Japan

[25] Rakuwakai Otowa Hosp, Dept Neurosurg, Kyoto, Kyoto, Japan

[26] Rakuwakai Otowa Hosp, Normal Pressure Hydrocephalus Ctr, Kyoto, Kyoto, Japan

来源：

NEUROLOGIA MEDICO-CHIRURGICA | 2021年 / 61卷 / 02期

关键词：

clinical guideline; idiopathic normal pressure hydrocephalus; diagnosis; treatment; management; CSF TAP-TEST; CEREBROSPINAL-FLUID BIOMARKERS; PROGRAMMABLE SHUNT VALVES; WHITE-MATTER LESIONS; PHASE-CONTRAST MRI; CEREBRAL METABOLIC-RATE; QUICK REFERENCE TABLE; INTRACRANIAL-PRESSURE; ADULT HYDROCEPHALUS; PREDICTIVE-VALUE;

D O I：

10.2176/nmc.st.2020-0292

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Among the various disorders that manifest with gait disturbance, cognitive impairment, and urinary incontinence in the elderly population, idiopathic normal pressure hydrocephalus (iNPH) is becoming of great importance. The first edition of these guidelines for management of iNPH was published in 2004, and the second edition in 2012, to provide a series of timely, evidence-based recommendations related to iNPH. Since the last edition, clinical awareness of iNPH has risen dramatically, and clinical and basic research efforts on iNPH have increased significantly. This third edition of the guidelines was made to share these ideas with the international community and to promote international research on iNPH. The revision of the guidelines was undertaken by a multidisciplinary expert working group of the Japanese Society of Normal Pressure Hydrocephalus in conjunction with the Japanese Ministry of Health, Labour and Welfare research project. This revision proposes a new classification for NPH. The category of iNPH is clearly distinguished from NPH with congenital/developmental and acquired etiologies. Additionally, the essential role of disproportionately enlarged subarachnoid-space hydrocephalus (DESH) in the imaging diagnosis and decision for further management of iNPH is discussed in this edition. We created an algorithm for diagnosis and decision for shunt management. Diagnosis by biomarkers that distinguish prognosis has been also initiated. Therefore, diagnosis and treatment of iNPH have entered a new phase. We hope that this third edition of the guidelines will help patients, their families, and healthcare professionals involved in treating iNPH.

引用

页码：63 / 97

页数：35

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