Spectrophotometric determination of valacyclovir in pharmaceutical formulation

被引:0
|
作者
Babu, G. Srinu [1 ]
Babu, I. Sarat [1 ]
Kumar, N. Kiran [1 ]
Yugandhar, N. M. [1 ]
Raju, Ch. A. I. [1 ]
机构
[1] Andhra Univ, Dept Chem Engn, Visakhapatnam 530003, Andhra Pradesh, India
关键词
valacyclovir; UV spectrophotometry;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A Simple, sensitive, spectrophotometric method in UV region has been developed for the determination of valacyclovir in bulk and tablet dosage forms. Valacyclovir is a new antiviral drug, which shows maximum absorbance at 274 nm with apparent molar absorpitivity of 2.69167 x 10(4) L/molcm. Beer's law was obeyed in the concentration range of 5-50 mu g/mL. Results of the analysis were validated statistically and by recovery studies.
引用
收藏
页码:1642 / 1644
页数:3
相关论文
共 50 条
  • [1] Spectrophotometric determination of valacyclovir hydrochloride in bulk and pharmaceutical formulations
    Reddy, D. V. Prasad
    Gurupadayya, B. M.
    Manohara, Y. N.
    Bhaskar, V. Vuaya
    ASIAN JOURNAL OF CHEMISTRY, 2007, 19 (04) : 2797 - 2800
  • [2] Spectrophotometric determination of flutamide in pharmaceutical formulation
    Rao, GD
    ASIAN JOURNAL OF CHEMISTRY, 2004, 16 (3-4) : 1769 - 1772
  • [3] Spectrophotometric determination of etidocaine in pharmaceutical (dental) formulation
    Silva, N
    Schapoval, EES
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2002, 29 (04) : 749 - 754
  • [4] Spectrophotometric Determination of Gemifloxacin in Bulk and Pharmaceutical Formulation
    Ganapathy, S.
    Raju, G. V. H.
    Sankar, D. G.
    Naidu, Pettla Y.
    ASIAN JOURNAL OF CHEMISTRY, 2009, 21 (08) : 6508 - 6512
  • [5] Kinetic spectrophotometric determination of tramadol hydrochloride in pharmaceutical formulation
    Abdellatef, HE
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2002, 29 (05) : 835 - 842
  • [6] UV Spectrophotometric Determination of Aripiprazole in Bulk and Pharmaceutical Formulation
    Kalaichelvi, R.
    Thangabalan, B.
    Rao, D. Srinivasa
    Jayachandran, E.
    E-JOURNAL OF CHEMISTRY, 2009, 6 : S87 - S90
  • [7] Spectrophotometric Determination of Adefovir Dipivoxil in bulk and Pharmaceutical Formulation
    Ahmed, Zaheer
    Manohara, Y. N.
    Channabasawaraj, K. P.
    Majumdar, Manish
    E-JOURNAL OF CHEMISTRY, 2008, 5 (04) : 713 - 717
  • [8] SPECTROPHOTOMETRIC DETERMINATION OF CORTICOSTEROIDS AND ITS APPLICATION IN PHARMACEUTICAL FORMULATION
    Singh, D. K.
    Verma, R.
    OXIDATION COMMUNICATIONS, 2009, 32 (03): : 678 - 684
  • [9] UV spectrophotometric determination of oxaprozin in pure and pharmaceutical formulation
    Ganesh, M.
    Thangabalan, B.
    Thakur, Dinesh
    Srinivasan, K.
    Ganguly, Swstika
    Sivakumar, T.
    ASIAN JOURNAL OF CHEMISTRY, 2008, 20 (07) : 5451 - 5454
  • [10] Spectrophotometric determination of gatifloxacin in pure form and in pharmaceutical formulation
    Amin, Alaa S.
    Gouda, Ayman Abou El-Fetouh
    El-Sheikh, Ragaa
    Zahran, Faten
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2007, 67 (05) : 1306 - 1312