The reaction of isoquinoline and dimethyl acetylenedicarboxylate with 1,2-and 1,4-benzoquinones:: a novel synthesis of spiro[1,3]oxazino[2,3-a]isoquinolines

被引：68
|
作者：
Nair, V [1 ]
Sreekanth, AR
Biju, AT
Rath, NP
机构：
[1] CSIR, Reg Res Lab, Div Organ Chem, Trivandrum 695019, Kerala, India
[2] Univ Missouri, Dept Chem, St Louis, MO 63121 USA
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 04期
关键词：
D O I：
10.1016/S0040-4039(02)02649-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The 1,4-dipolar intermediate generated by the addition of isoquinoline to dimethyl acetylenedicarboxylate is trapped by 1,2- and 1,4-benzoquinones to afford spiro[1,3]oxazino[2,3-a]isoquinoline derivatives in high yields. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：729 / 732
页数：4
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