Classical genetic studies involving the analysis of pedigrees and recurrence risk within families have defined the extent to which genetic factors contribute to the aetiology of multiple sclerosis. Limited progress has been made in identifying the number and topography of genetic loci contributing to susceptibility through molecular investigation either of candidate genes or the whole genome using microsatellite and single nucleotide polymorphisms.
机构:
Univ Calif San Francisco, Sch Med, Dept Neurol, San Francisco, CA 94143 USAUniv Calif San Francisco, Sch Med, Dept Neurol, San Francisco, CA 94143 USA
Oksenberg, JR
Hauser, SL
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Sch Med, Dept Neurol, San Francisco, CA 94143 USAUniv Calif San Francisco, Sch Med, Dept Neurol, San Francisco, CA 94143 USA
机构:
Univ Calif San Francisco, Dept Neurol, 675 Nelson Rising Lane, San Francisco, CA 94158 USAUniv Calif San Francisco, Dept Neurol, 675 Nelson Rising Lane, San Francisco, CA 94158 USA
Canto, Ester
Oksenberg, Jorge R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Dept Neurol, 675 Nelson Rising Lane, San Francisco, CA 94158 USAUniv Calif San Francisco, Dept Neurol, 675 Nelson Rising Lane, San Francisco, CA 94158 USA