New Therapy Approaches for Parkinson's Disease

被引:0
|
作者
Brockmann, K. [1 ]
Berg, D. [1 ,2 ]
机构
[1] Univ Tubingen, Deutsch Zentrum Neurodegenerat Erkrankungen, Hertie Inst Klin Hirnforsch, Abt Neurodegenerat,Zentrum Neurol, Hoppe Seyler Str 3, D-72076 Tubingen, Germany
[2] Univ Kiel, Klin Neurol, Kiel, Germany
来源
NERVENARZT | 2017年 / 88卷 / 04期
关键词
GLUCOCEREBROSIDASE MUTATIONS; TNF-ALPHA; PD; MARKERS; ASSOCIATION; PROGRESSION; IRON; IL-6;
D O I
10.1007/s00115-017-0299-x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Over the last years major advances have been made in the identification of specific pathways underlying the pathophysiology of subgroups of patients with Parkinson’ disease. These pathways include mitochondrial and lysosomal dysfunction as well as inflammatory patterns and represent the basis for new causative and disease-modifying treatment strategies, possibly not only for the respective subgroups of patients but hopefully also for the majority of patients with idiopathic Parkinson’s disease. This article highlights the main treatment strategies focusing on causative and disease course-modifying strategies as well as quality of life. © 2017, Springer Medizin Verlag GmbH.
引用
收藏
页码:391 / 396
页数:6
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