SNXs take center stage in endosomal sorting

被引：6
|
作者：
Hong, Wanjin [1 ]
机构：
[1] ASTAR, Inst Mol & Cell Biol, Singapore, Singapore
来源：
NATURE CELL BIOLOGY | 2019年 / 21卷 / 10期
关键词：
CARGO RECOGNITION;
D O I：
10.1038/s41556-019-0401-7
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Endosomes are central stations for converging proteins from biosynthetic pathways and endocytic routes. Many endosomal proteins are sorted to the plasma membrane or the Golgi despite the lysosome being the primary endosomal fate. SNX5 and SNX6 are now revealed to decode a conserved bipartite signal to mediate protein sorting to the Golgi or the plasma membrane.
引用
收藏
页码：1175 / 1177
页数：3
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