Role of Imaging in the Era of Precision Medicine

被引:43
|
作者
Giardino, Angela [1 ,2 ]
Gupta, Supriya [3 ]
Olson, Emmi [4 ]
Sepulveda, Karla [5 ]
Lenchik, Leon [6 ]
Ivanidze, Jana [7 ]
Rakow-Penner, Rebecca [8 ]
Patel, Midhir J. [9 ]
Subramaniam, Rathan M. [10 ]
Ganeshan, Dhakshinamoorthy [11 ]
机构
[1] Brigham & Womens Hosp, Dana Farber Canc Inst, Dept Imaging, 75 Francis St, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Dept Radiol, 75 Francis St, Boston, MA 02115 USA
[3] Med Coll Georgia, Dept Radiol & Imaging, 1120 15th St, Augusta, GA 30912 USA
[4] Univ Calif San Diego, San Diego, CA 92103 USA
[5] Baylor Coll Med, Houston, TX 77030 USA
[6] Wake Forest Sch Med, Dept Radiol, Winston Salem, NC USA
[7] Weill Cornell Med, Dept Diagnost Radiol, New York, NY USA
[8] Univ Calif San Diego, Dept Radiol, San Diego, CA 92103 USA
[9] Univ S Florida, Dept Radiol, Tampa, FL USA
[10] UT Southwestern Med Ctr, Dept Radiol, Cyclotron & Mol Imaging Program, Dallas, TX USA
[11] Univ Texas MD Anderson Canc Ctr, Dept Diagnost Radiol, Houston, TX 77030 USA
关键词
Precision medicine; imaging in oncology; task force; MAGNETIC-RESONANCE-SPECTROSCOPY; APPARENT DIFFUSION-COEFFICIENT; SIGNIFICANT PROSTATE-CANCER; RECURRENCE-FREE SURVIVAL; BREAST-CANCER; LUNG-CANCER; TEXTURE ANALYSIS; MOLECULAR SUBTYPES; CELL-CARCINOMA; NEOADJUVANT CHEMORADIOTHERAPY;
D O I
10.1016/j.acra.2016.11.021
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Precision medicine is an emerging approach for treating medical disorders, which takes into account individual variability in genetic and environmental factors. Preventive or therapeutic interventions can then be directed to those who will benefit most from targeted interventions, thereby maximizing benefits and minimizing costs and complications. Precision medicine is gaining increasing recognition by clinicians, healthcare systems, pharmaceutical companies, patients, and the government. Imaging plays a critical role in precision medicine including screening, early diagnosis, guiding treatment, evaluating response to therapy, and assessing likelihood of disease recurrence. The Association of University Radiologists Radiology Research Alliance Precision Imaging Task Force convened to explore the current and future role of imaging in the era of precision medicine and summarized its finding in this article. We review the increasingly important role of imaging in various oncological and non-oncological disorders. We also highlight the challenges for radiology in the era of precision medicine. Published by Elsevier Inc. on behalf of The Association of University Radiologists.
引用
收藏
页码:639 / 649
页数:9
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