Two-Year Prevalence of Rotavirus Among Under-Five Children Admitted with Acute Gastroenteritis in Andhra Pradesh, India

被引：2
|
作者：
Goru, Krishna Babu [1 ]
Manikyamba, D. [2 ]
Muppidi, Vineela Priyanka [1 ]
Nadipena, Jhansi [1 ]
Ravula, Mahalakshmi [3 ]
Babji, K. [3 ]
Kumar, Ranjith [4 ]
Reddy, Samarasimha N. [4 ]
机构：
[1] Rangaraya Med Coll, Dept Community Med, Kakinada 533001, Andhra Pradesh, India
[2] Rangaraya Med Coll, Dept Pediat, Kakinada, Andhra Pradesh, India
[3] Rangaraya Med Coll, Dept Surg, Kakinada, Andhra Pradesh, India
[4] Christian Med Coll & Hosp, Wellcome Trust Res Lab, Vellore, Tamil Nadu, India
来源：
INDIAN JOURNAL OF PEDIATRICS | 2021年 / 88卷 / SUPPL 1期
关键词：
Under-five; Rotavirus; Acute gastroenteritis; Immunization; Genotypes; STRAINS; DISEASE; DIVERSITY; DIARRHEA;
D O I：
10.1007/s12098-020-03608-1
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Objective To estimate the burden of rotavirus diarrhea among under-five children admitted with acute gastroenteritis and to identify genotypes of rotavirus among positive rotavirus cases. Methods This is a cross-sectional study conducted from August 2017 to July 2019 in Government General Hospital and 5 private pediatric nursing homes (Padma Children's Hospital, Mother and Child Hospital, Chandamama Children's Hospital, Vennela Hospital) in Kakinada. Children admitted to the pediatric ward with acute gastroenteritis were included in this study. Stool samples were collected from all these children and tested for rotavirus by enzyme-linked immunosorbent assay and the positive samples were genotyped using reverse transcriptase polymerase chain reaction. Results Rotavirus diarrhea was seen in 7.4% of children among all diarrhea admissions. The mean age of the rotavirus-positive children was 13.1 +/- 10 mo. The most common genotype in 2017 was G3P[8], and that in 2018 and 2019 was the mixed genotype. Conclusion In this study, mixed genotype was found to be most common.
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页码：72 / 77
页数：6
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