What should we tell parents? Congenital diaphragmatic hernia

被引：14

作者：

Russo, Francesca M. ^{[1
,2
]}

Debeer, Anne ^{[2
,3
]}

De Coppi, Paolo ^{[4
,5
]}

Devriendt, Koenraad ^{[6
]}

Crombag, Neeltje ^{[2
]}

Hubble, Talia ^{[2
,7
]}

Power, Beverley ^{[8
]}

Benachi, Alexandra ^{[9
,10
]}

Deprest, Jan ^{[1
,2
,11
]}

机构：

[1] Univ Hosp Leuven, Clin Dept Obstet & Gynaecol, Leuven, Belgium

[2] Katholieke Univ Leuven, Acad Dept Dev & Regenerat Cluster Woman & Child, Leuven, Belgium

[3] Univ Hosp Leuven, Neonatal Intens Care Unit, Leuven, Belgium

[4] Great Ormond St Hosp Sick Children, Neonatal & Paediat Surg Unit, London, England

[5] UCL Great Ormond St Inst Child Hlth, NIHR Biomed Res Ctr, Stem Cells & Regenerat Med Sect, London, England

[6] Univ Hosp Leuven, Ctr Human Genet, Leuven, Belgium

[7] Univ Oxford, Med Sci Div, Oxford, England

[8] CDH UK, Kings Lynn, England

[9] Univ Paris Saclay, Dept Obstet & Gynecol, Hop Antoine Beclere, HP, Clamart, France

[10] Ctr Reference Malad Rare Hernie Coupole Diaphragm, Clamart, France

[11] UCL, Inst Womens Hlth, London, England

来源：

PRENATAL DIAGNOSIS | 2022年 / 42卷 / 03期

关键词：

EXTRACORPOREAL MEMBRANE-OXYGENATION; HEAD CIRCUMFERENCE RATIO; THORACIC VOLUME RATIO; LIVER HERNIATION; PULMONARY-HYPERTENSION; NEONATAL MORBIDITY; POSTNATAL SURVIVAL; PRENATAL-DIAGNOSIS; LUNG-VOLUME; FETAL MRI;

D O I：

10.1002/pd.5880

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Congenital diaphragmatic hernia (CDH) is characterized by a defect in the muscle dividing the thoracic and abdominal cavities. This leads to herniation of the abdominal organs into the thorax and a disturbance of lung development. Two-thirds of cases are identified by prenatal ultrasound in the second trimester, which should prompt referral to a tertiary center for prognosis assessment and counseling by a multidisciplinary team familiar with this condition. In this review, we summarize evidence on prenatal diagnosis and postnatal management of CDH. There is a focus on information that should be provided to expecting parents during prenatal counseling.

引用

页码：398 / 407

页数：10

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