Acute effect of stretching one leg on regional arterial stiffness in young men

Purpose Our previous study demonstrated that a single bout of stretching exercises acutely reduced arterial stiffness. We hypothesized that this acute vascular response is due to regional mechanical stimulation of the peripheral arteries. To test this hypothesis, we examined the effect of a single bout of passive one leg stretching on arterial stiffness, comparing the stretched and the non-stretched leg in the same subject. Methods Twenty-five healthy young men (20.9 +/- 0.3 years, 172.5 +/- 1.4 cm, 64.1 +/- 1.2 kg) volunteered for the study. Subjects underwent a passive calf stretching on one leg (six repetitions of 30-s static stretch with a 10-s recovery). Pulse wave velocity (PWV, an index of arterial stiffness), blood pressure (BP), and heart rate (HR) were measured before and immediately, 15, and 30 min after the stretching. Results Femoral-ankle PWV (faPWV) in the stretched leg was significantly decreased from baseline (835.0 +/- 15.9 cm/s) to immediately (802.9 +/- 16.8 cm/s, P < 0.01) and 15 min (810.5 +/- 16.0 cm/s, P < 0.01) after the stretching, despite no changes in systolic and diastolic BP, or HR. However, faPWV in the non-stretched leg was not significantly altered at any time. Brachial-ankle PWV (baPWV) also showed similar responses with faPWV, but this response was not significant. Additionally, the passive stretching did not alter carotid-femoral PWV (cfPWV). Conclusions These results suggest that mechanical stimulation to peripheral arteries as induced by static passive stretch may modulate arterial wall properties directly, rather than resulting in a systemic effect.