Study on the interaction of sodium deoxycholate with supported bilayer lipid membrane by electrochemistry method

被引：0

作者：

Wang Jian-Guo ^{[1
]}

Jiang Li-Li ^{[1
]}

Hui Fei ^{[1
]}

Yang Wei-Wei ^{[1
]}

Lu Hui ^{[1
]}

Sun Qiao-Hua ^{[1
]}

机构：

[1] Liaoning Univ, Inst Chem Sci & Engn, Shenyang 110036, Peoples R China

来源：

ACTA CHIMICA SINICA | 2007年 / 65卷 / 03期

关键词：

supported bilayer lipid membrane; cyclic voltammetry; ac impedance spectroscopy; sodium deoxycholate;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this paper, supported bilayer lipid membrane (s-BLM) was served as a biomembrane model. The interaction between sodium deoxycholate (NaDC) and s-BLM was investigated by means of cyclic voltammetry and ac impedance spectroscopy. The results show that NaDC can decrease the orderliness of lecithin molecule and induce pores or defects on s-BLM. The interaction between them depends on time, concentration, pH and cholesterol. The defective s-BLM after interaction can be self-repaired in 0.1 mol/L KCl solution, which indicates that the interaction is reversible.

引用

页码：239 / 245

页数：7

共 35 条

[1] Mixed micelles and other structures in the solubilization of bilayer lipid membranes by surfactants
Almgren, M
[J]. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2000, 1508 (1-2): : 146 - 163
[2] INTERACTION OF DETERGENTS WITH BILAYER LIPID-MEMBRANES
BANGHAM, JA
LEA, EJA
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1978, 511 (03) : 388 - 396
[3] BARD AJ, 1980, ELECTROCHEMICAL METH, P501
[4] Deoxycholate alters the order of acyl chains in freeze-thaw extrusion vesicles of L-alpha-dipalmitoyl phosphatidylcholine: Study of the 1,6-diphenyl-1,3,5-hexatriene steady-state fluorescence anisotropy
Chantres, JR
Elorza, B
Elorza, MA
Rodado, P
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1996, 138 (02) : 139 - 148
[5] The influence of absorption enhancers on nasal absorption of acyclovir
Chavanpatil, MD
Vavia, PR
[J]. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2004, 57 (03) : 483 - 487
[6] DIAO P, 1999, CHIN ELECTROCHEM, V5, P288
[7] INFLUENCE OF SOME SURFACE-ACTIVE AGENTS ON NASAL ABSORPTION IN RABBITS
DUCHATEAU, GSMJE
ZUIDEMA, J
BASSELEUR, SWJ
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1987, 39 (1-2) : 87 - 92
[8] Stability of liposomal formulations: action of amphiphilic molecules
Elorza, MA
Elorza, B
Chantres, JR
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1997, 158 (02) : 173 - 183
[9] Membrane supported bilayer lipid membranes array: preparation, stability and ion-channel insertion
Favero, G
D'Annibale, A
Campanella, L
Santucci, R
Ferri, T
[J]. ANALYTICA CHIMICA ACTA, 2002, 460 (01) : 23 - 34
[10] THICKNESS, COMPOSITION AND STRUCTURE OF SOME LIPID BILAYERS AND NATURAL MEMBRANES
FETTIPLACE, R
ANDREWS, DM
HAYDON, DA
[J]. JOURNAL OF MEMBRANE BIOLOGY, 1971, 5 (03): : 277 - +

← 1 2 3 4 →