Kinesin motors and disease

被引：103
|
作者：
Mandelkow, E [1 ]
Mandelkow, EM [1 ]
机构：
[1] Max Planck Unit Struct Mol Biol, D-22607 Hamburg, Germany
来源：
TRENDS IN CELL BIOLOGY | 2002年 / 12卷 / 12期
关键词：
D O I：
10.1016/S0962-8924(02)02400-5
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Kinesins are motor proteins that move cargoes such as vesicles, organelles and chromosomes along microtubules. They are best known for their role in axonal transport and in mitosis. There is a diverse family of kinesins, members of which differ in composition and functions. Roles of kinesins in diseases typically involve defective transport of cell components, transport of pathogens, or cell division.
引用
收藏
页码：585 / 591
页数：7
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