Examine the Prevalence of H. Pylori Infection Also Determine the Accuracy of Rapid Urease Test and Histopathology Examination for Diagnosing H. Pylori Infection

Aim: To examine the accuracy of RUT and compare with histopathology examination to diagnose H. pylori infection in patients presented with gastritis Study design: Prospective/Observational study Place & duration: Department of Pathology Shahida Islam Medical College Lodhran from 1st March 2016 to 31st January 2017 Methods: A total 120 patients of both genders with ages 20 to 70 years having gastritis were included in this study. Four biopsies were taken from all the patients 2 biopsies were taken for the RUT and 2 for the histopathology examination. Sensitivity, specificity, PPV and NPV were examined of both methods. Results: Out of 120 patients 57 (47.5%) patients were males while 52.5% patients were females. 80 (66.67%) patients had H.pylori infection by Rapid urease test and 79 (65.83%) patients had H pylori infection as per histopathology examination. Association between RUT and Histopathology examination were noted as sensitivity, specificity, PPV and NPV as 96.20%, 92.5%, 95% and 90.24% respectively. Conclusion: It is concluded from this study that rapid urease test shows accurate results with no procedural complications. It is a good alternative to histopathology examination in patients presented with gastritis.