MODERN TRENDS IN MORTALITY FROM MENINGOCOCCAL DISEASE IN AUSTRALIA

被引：10

作者：

Simpkins, Daniel ^{[2
,3
]}

Wood, Nicholas ^{[1
]}

Jelfs, Jane ^{[1
]}

McIntyre, Peter B. ^{[1
,2
,3
]}

Menzies, Robert ^{[1
]}

Lawrence, Glenda ^{[5
]}

Booy, Robert ^{[1
,2
,3
,4
]}

机构：

[1] Childrens Hosp Westmead, Natl Ctr Immunizat Res & Surveillance Vaccine Pre, Westmead, NSW 2145, Australia

[2] Univ Sydney, Discipline Paediat & Child Hlth, Sydney, NSW 2006, Australia

[3] Univ Sydney, Sch Publ Hlth, Sydney, NSW 2006, Australia

[4] Queen Mary Univ London, Barts & London Sch Med & Dent, Acad Unit Child Hlth, London, England

[5] Univ New S Wales, Fac Med, Sch Publ Hlth & Community Med, Sydney, NSW, Australia

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2009年 / 28卷 / 12期

关键词：

meningococcal disease; mortality; vaccine;

D O I：

10.1097/INF.0b013e3181accde8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Between 1979 and 2006, there were 610 deaths recorded as due to meningococcal disease in Australia. Mortality rates per capita consistently increased on average by 6% per annum between 1979 and 2002, but then fell significantly in 2003, coinciding with the introduction of the meningococcal C conjugate vaccine. In 2002, the mortality rate was 0.24 per 100,000. In the 4 years since, it fell progressively to 0.06 per 100,000. Since the introduction of conjugate Hib and pneumococcal vaccines, meningococcal disease has emerged as the number 1 infectious cause of death in children but conjugate meningococcal C vaccine appears to have greatly reduced total meningococcal disease deaths.

引用

页码：1119 / 1120

页数：2

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