MiR-144-3p inhibits the proliferation, migration and invasion of lung adenocargen cancer cells by targeting COL11A1

被引:9
|
作者
Sun, Yahong [1 ]
Liu, Zhihao [1 ]
Huang, Lifei [1 ]
Shang, Yan [2 ]
机构
[1] Dept Haining Peoples Hosp, Lung & CriticalLy Ill Emergency Med, Haining, Peoples R China
[2] Second Mil Med Univ, Changhai Hosp, Dept Naval Med Univ, Resp & Crit Emergency Med, Shanghai, Peoples R China
基金
中国国家自然科学基金;
关键词
miR-144-3p; COL11A1; lung adenocarcinoma; proliferation; migration and invasion; metastasis-related gene; TUMOR-SUPPRESSOR; COLLAGEN;
D O I
10.1080/1120009X.2021.1906031
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This study aimed to investigate the regulatory relationship between miR-144-3p and COL11A1, and to explore its effect on the proliferation, migration and invasion of lung adenocarcinoma (LUAD) cells. A series of methods and experiments were applied. miR-144-3p was downregulated in LUAD tissue and cells, whereas COL11A1 was highly expressed. Overexpressing miR-144-3p inhibited the proliferation, migration and invasion of LUAD cells, which could be reversed by overexpression of COL11A1. Overexpressing miR-144-3p inhibits the proliferation, migration and invasion of LUAD cells by silencing COL11A1.
引用
收藏
页码:409 / 419
页数:11
相关论文
共 50 条
  • [1] MiR-144-3p inhibits the proliferation and metastasis of lung cancer A549 cells via targeting HGF
    Guiju Fang
    Canhui Zhang
    Zhixin Liu
    Zhiwen Peng
    Meiyan Tang
    Qing Xue
    [J]. Journal of Cardiothoracic Surgery, 17
  • [2] MiR-144-3p inhibits the proliferation and metastasis of lung cancer A549 cells via targeting HGF
    Fang, Guiju
    Zhang, Canhui
    Liu, Zhixin
    Peng, Zhiwen
    Tang, Meiyan
    Xue, Qing
    [J]. JOURNAL OF CARDIOTHORACIC SURGERY, 2022, 17 (01)
  • [3] SPP1 facilitates cell migration and invasion by targeting COL11A1 in lung adenocarcinoma
    Xuan Yi
    Linlin Luo
    Yanzhen Zhu
    Hong Deng
    Huitian Liao
    Yang Shen
    Yan Zheng
    [J]. Cancer Cell International, 22
  • [4] SPP1 facilitates cell migration and invasion by targeting COL11A1 in lung adenocarcinoma
    Yi, Xuan
    Luo, Linlin
    Zhu, Yanzhen
    Deng, Hong
    Liao, Huitian
    Shen, Yang
    Zheng, Yan
    [J]. CANCER CELL INTERNATIONAL, 2022, 22 (01)
  • [5] Sevoflurane inhibits neuroblastoma cell proliferation and invasion and induces apoptosis by miR-144-3p/YAP1 axis
    Yang, Longqiu
    He, Ke
    Yao, Shudong
    Zhang, Yiqiang
    Shen, Jun
    [J]. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2021, 129 (04) : 297 - 307
  • [6] MiR-144-3p regulates invasion and proliferation activity in hepatocellular carcinoma by targeting SLITRK4
    Xiao, D. B.
    Xu, H.
    Li, J. C.
    Peng, K. K.
    Jiang, X. L.
    Wang, D. X.
    Zhu, F. F.
    [J]. INTERNATIONAL JOURNAL OF RADIATION RESEARCH, 2024, 22 (02): : 361 - 366
  • [7] MiR-144-3p inhibits the proliferation and metastasis of pediatric Wilms' tumor cells by regulating Girdin
    Liu, C-L
    Wang, W-H
    Sun, Y-L
    Zhuang, H-W
    Xu, M.
    Chen, H-F
    Liu, J-X
    [J]. EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2018, 22 (22) : 7671 - 7678
  • [8] miR-144-3p inhibits cell proliferation of colorectal cancer cells by targeting BCL6 via inhibition of Wnt/β-catenin signaling
    Sun, Naihui
    Zhang, Liang
    Zhang, Chongguang
    Yuan, Yuan
    [J]. CELLULAR & MOLECULAR BIOLOGY LETTERS, 2020, 25 (01)
  • [9] RETRACTED: Tetramethylpyrazine Inhibits the Proliferation and Invasion of Glioma Cells by Regulating the UBL7-AS1/miR-144-3p Pathway (Retracted Article)
    Liang, Rui
    Zhang, Guofeng
    Xu, Wenhua
    Liu, Weibing
    Tang, Youjia
    [J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2022, 2022
  • [10] COL11A1 Was Involved in Cell Proliferation, Apoptosis and Migration in Non-Small Cell Lung Cancer Cells
    Tu, Hongbin
    Li, Jing
    Lin, Lei
    Wang, Lixin
    [J]. JOURNAL OF INVESTIGATIVE SURGERY, 2021, 34 (06) : 664 - 669