Factors Associated with Anticoagulation Adherence in Chinese Patients with Non-Valvular Atrial Fibrillation

被引:7
|
作者
Song, Ting [1 ]
Xin, Xiao [2 ]
Cui, Peirong [1 ]
Zong, Mingcan [1 ]
Li, Xianhua [3 ]
机构
[1] Shanghai Jiao Tong Univ, Sch Nursing, Shanghai, Peoples R China
[2] Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Oncol, Sch Med, Shanghai, Peoples R China
[3] Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Outpatient Off, Sch Med, Shanghai, Peoples R China
来源
关键词
atrial fibrillation; medication adherence; anticoagulation; non-vitamin K antagonist oral anticoagulants; determinants; MEDICATION USE SCALE; SELF-EFFICACY; RISK; METAANALYSIS; PERSISTENCE; WARFARIN; THERAPY; STROKE; IMPACT;
D O I
10.2147/PPA.S285020
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose: Inadequate medication adherence among patients with non-valvular atrial fibrillation (NVAF) will directly affect the efficacy and safety of anticoagulation therapy, leading to a considerable increase in the risk of ischemic stroke and death. In this study, we aim to investigate medication adherence and identify the influencing factors, including social-demographic, disease-related information and self-efficacy. Patients and Methods: We recruited 170 patients with NVAF from a tertiary hospital atrial fibrillation outpatient clinics and cardiology ward from June 2020 to September 2020. Patients who had been taking oral anticoagulation medication for at least 3 months were included. And Morisky medication adherence scale (MGL) was used to assess the adherence to anticoagulants, which scores <4 were considered as low adherence. Results: Fifty (29.4%) NVAF patients had a MGL score<4. Monthly income, types of comorbidities, number of drugs, and self-efficacy were determinants of anticoagulation adherence. Binomial logistic regression showed that patients had been prescribed more durgs (OR: 3.51, p=0.002), had high monthly income (OR: 7.87, p=0.001), without other diseases (OR: 8.00, p=0.005), and with higher self-efficacy (OR: 1.42, p=0.001) showed high adherence. Conclusion: Number of drugs, types of comorbidities, monthly income, and self-efficacy were associated with the adherence of non-vitamin K antagonist oral anticoagulants (NOACs).
引用
收藏
页码:493 / 500
页数:8
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