Effects of cilazapril on endothelial function and pulmonary hypertension in patients with congestive heart failure

被引：7
|
作者：
Tavli, T [1 ]
Gocer, H [1 ]
机构：
[1] Celal Bayer Univ, Sch Med, Dept Cardiol, Izmir, Turkey
来源：
JAPANESE HEART JOURNAL | 2002年 / 43卷 / 06期
关键词：
endothelial function; cilazapril; pulmonary hypertension; congestive heart failure;
D O I：
10.1536/jhj.43.667
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Flow-mediated vasodilation (FMV), brachial artery flow (BAF), and brachial artery diameter were evaluated in 30 patients with congestive heart failure before and after cilazapril treatment. While mean pulmonary artery pressure and Pulmonary capillary wedge pressure decreased significantly, flow-mediated vasodilation and left ventricular ejection fraction increased significantly following cilazapril administration (P<0.001). Brachial artery diameter and brachial artery flow did not change following the treatment period (P>0.05). In conclusion, short term cilazapril administration improved endothelial function and pulmonary pressure in patients with congestive heart failure.
引用
收藏
页码：667 / 674
页数：8
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