Monitoring the antioxidant activity of extracts originated from various Serratula species and isolation of flavonoids from Serratula coronata

被引：22
|
作者：
Báthori, M
Zupkó, I
Hunyadi, A
Gácsné-Baitz, E
Dinya, Z
Forgó, P
机构：
[1] Univ Szeged, Dept Pharmacognosy, H-6720 Szeged, Hungary
[2] Univ Szeged, Dept Pharmacodynam & Biopharm, H-6720 Szeged, Hungary
[3] Univ Debrecen, Inst Organ Chem, H-4010 Debrecen, Hungary
[4] Univ Szeged, Dept Organ Chem, H-6720 Szeged, Hungary
来源：
FITOTERAPIA | 2004年 / 75卷 / 02期
基金：
匈牙利科学研究基金会;
关键词：
Serratula coronata; Serratula spp; antioxidant activity; flavonoid;
D O I：
10.1016/j.fitote.2003.12.009
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The antioxidant effect of aqueous methanolic herb extracts of Serratula coronata, S. wolffli and S. tinctoria was investigated using both enzyme-dependent and enzyme-independent systems. The extracts displayed concentration-dependent inhibition of lipid peroxidation. Flavonoids and ecdysteroids present in the extracts were evaluated as antioxidant components. The flavonoid-containing fraction of the herb extract of S. coronata was more effective in lipid peroxidation than the ecdysteroid-containing fraction. This paper also reports the isolation of quercetin 3-O-methyl ether, apigenin, luteolin, quercetin, luteolin 4'beta-D-glucoside and quercetin 4'beta-D-glucoside from S. coronata. (C) 2003 Elsevier B.V. All rights reserved.
引用
收藏
页码：162 / 167
页数：6
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