A biochip based on magnetoresistive sensors

被引:70
|
作者
Schotter, J [1 ]
Kamp, PB
Becker, A
Pühler, A
Brinkmann, D
Schepper, W
Brückl, H
Reiss, G
机构
[1] Univ Bielefeld, Dept Phys, D-33615 Bielefeld, Germany
[2] Univ Bielefeld, Dept Biol, D-33615 Bielefeld, Germany
关键词
bioniagneties; biomedical measurements; magnetoresistive devices; sensors;
D O I
10.1109/TMAG.2002.802290
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
The signal response of Bangs Laboratories magnetic markers with a mean diameter of 0.86 mum on a spiral-shaped giant magnetoresistance sensor with a diameter of 70 mum is investigated. The data show a linear dependence of the sensor signal on the surface coverage of the magnetic markers. The detection limit is reached at a coverage of about 5%, which corresponds to about 200 markers distributed across the surface of the sensor. The corresponding molecular binding of the analyte DNA and the magnetic markers show good selectivity and sensitivity.
引用
收藏
页码:3365 / 3367
页数:3
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