Incidence of myeloproliferative neoplasms in Calgary, Alberta, Canada

被引：9

作者：

Heppner, Jonathan ^{[1
]}

Nguyen, Leonard Tu ^{[2
]}

Guo, Maggie ^{[2
,3
]}

Naugler, Christopher ^{[2
,3
,4
,5
]}

Rashid-Kolvear, Fariborz ^{[2
,3
,6
]}

机构：

[1] Univ Saskatchewan, Coll Med, Saskatoon, SK, Canada

[2] Univ Calgary, Cumming Sch Med, Dept Pathol & Lab Med, Calgary, AB, Canada

[3] Alberta Publ Labs, Calgary, AB, Canada

[4] Univ Calgary, Cumming Sch Med, Dept Family Med, Calgary, AB, Canada

[5] Univ Calgary, Cumming Sch Med, Dept Community Hlth, Calgary, AB, Canada

[6] Univ Calgary, Cumming Sch Med, Dept Med Genet, Calgary, AB, Canada

来源：

BMC RESEARCH NOTES | 2019年 / 12卷 / 1期

基金：

加拿大健康研究院;

关键词：

EPIDEMIOLOGY; DIAGNOSIS; TRENDS;

D O I：

10.1186/s13104-019-4321-1

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

ObjectiveThe incidence of the combined myeloproliferative neoplasms (MPNs) was determined for a major Canadian city. Retrospective cases of MPN diagnoses (essential thrombocythemia, polycythemia vera, and primary myelofibrosis) between 2011 to 2015 were retrieved from the Southern Alberta Cancer Cytogenetics Laboratory's database at Alberta Public Laboratories.ResultsAn incidence rate of 2.05 cases per 100,000 person-years (95% CI 1.73-2.41) was determined, giving an age-standardized Canadian incidence of 2.71 cases per 100,000 person years (95% CI 2.63-2.78). MPN diagnoses occurred at a wide age range of 8-93 (median 66) and an age-dependent increase in incidence. Incidence rates for the MPNs are first reported here for a Canadian population.

引用

页数：5

共 50 条

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