X-Inactivation: Xist RNA Uses Chromosome Contacts to Coat the X

被引：4

作者：

Leung, Karen N. ^{[1
,2
]}

Panning, Barbara ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94158 USA

[2] Univ Calif San Francisco, Dept Anat, San Francisco, CA 94158 USA

来源：

CURRENT BIOLOGY | 2014年 / 24卷 / 02期

关键词：

METHYLATION; DOMAINS; GENES;

D O I：

10.1016/j.cub.2013.11.052

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mechanisms by which Xist RNA associates with the X chromosome to mediate alterations in chromatin structure remain mysterious. Recent genome-wide Xist RNA distribution studies suggest that this long noncoding RNA uses 3-dimensional chromosome contacts to move to its sites of action.

引用

页码：R80 / R82

页数：4

共 50 条

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