Life at the beginning: perturbation of the microbiota by antibiotics in early life and its role in health and disease

被引：171
|
作者：
Zeissig, Sebastian [1 ]
Blumberg, Richard S. [2 ]
机构：
[1] Univ Med Ctr Schleswig Holstein, Dept Internal Med, Kiel, Germany
[2] Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Gastroenterol Hepatol & Endoscopy, Boston, MA 02115 USA
来源：
NATURE IMMUNOLOGY | 2014年 / 15卷 / 04期
基金：
欧洲研究理事会; 美国国家卫生研究院;
关键词：
REGULATORY T-CELLS; GUT MICROBIOME; CHILDHOOD ASTHMA; ALLERGIC-ASTHMA; IMMUNE-SYSTEM; DELIVERY MODE; EXPOSURE; MICE; RISK; DIFFERENTIATION;
D O I：
10.1038/ni.2847
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
This Commentary discusses how treatment with antibiotics in infancy shapes host immunity and influences susceptibility later in life to diseases mediated by the immune system.
引用
收藏
页码：307 / 310
页数：4
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