Antigen valency dictates the affinity of B cells recruited to germinal centers and the magnitude of extrafollicular B cell responses

被引:0
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作者
Kato, Yu [1 ,2 ]
Groschel, Bettina [2 ,3 ,4 ]
Abbott, Robert K. [1 ,2 ]
Menis, Sergey [2 ,3 ,4 ]
Irvine, Darrell J. [5 ,6 ,7 ,8 ,9 ]
Schief, William R. [2 ,3 ,4 ,8 ]
Crotty, Shane [1 ,2 ,10 ]
机构
[1] La Jolla Inst Immunol, Div Vaccine Discovery, La Jolla, CA USA
[2] Scripps Res Inst, Consortium HIV AIDS Vaccine Dev, La Jolla, CA USA
[3] Scripps Res Inst, Dept Immunol & Microbiol, La Jolla, CA USA
[4] Scripps Res Inst, IAVI Neutralizing Antibody Ctr, La Jolla, CA USA
[5] MIT, Dept Biol Engn, Cambridge, MA 02139 USA
[6] MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA
[7] MIT, Dept Mat Sci & Engn, Cambridge, MA 02139 USA
[8] Ragon Inst MGH MIT & Harvard, Cambridge, MA USA
[9] Howard Hughes Med Inst, Chevy Chase, MD USA
[10] Univ Calif San Diego, Dept Med, Div Infect Dis & Global Publ Hlth, San Diego, CA 92103 USA
来源
JOURNAL OF IMMUNOLOGY | 2020年 / 204卷 / 01期
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中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
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页数:2
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