On reassessment of the chicken TGFB4 gene as TGFB1

被引：18

作者：

Halper, J ^{[1
]}

Burt, DW

Romanov, MN

机构：

[1] Univ Georgia, Coll Vet Med, Dept Pathol, Athens, GA 30602 USA

[2] Roslin Inst Edinburgh, Dept Genom & Bioinformat, Roslin EH25 9PS, Midlothian, Scotland

[3] Michigan State Univ, Dept Microbiol & Mol Genet, E Lansing, MI 48824 USA

来源：

GROWTH FACTORS | 2004年 / 22卷 / 02期

关键词：

D O I：

10.1080/08977190410001712878

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Three TGFB isoforms, TGFB1-3, are present in mammalian cells. The presence of four TGFB isoforms has been reported in avian species, though the sequence of TGFB4 was not conclusively determined. Our previously published data show that TGFB4 is actually the chicken ortholog of TGFB1. We mapped TGFB1 but not TGFB4 to linkage group E25C31 on GGA32 next to RYR1 forming a conserved segment with human chromosome HSA19q13.1-q13.2 and, therefore, being definitely the ortholog of human TGFB1. We, therefore, suggest that what was once called chicken "TGFB4" is actually TGFB1. Thus, in the evolutionary lineages of birds and mammals there are only three TGFB isoforms.

引用

页码：121 / 122

页数：2

共 50 条

[1] Genetic Association and Gene Expression Profiles of TGFB1 and the Contribution of TGFB1 to Otosclerosis Susceptibility
Priyadarshi, Saurabh
Ray, Chinmay Sundar
Panda, Khirod Chandra
Desai, Ashim
Nayak, Soumya Ranjan
Biswal, Narayan Chandra
Ramchander, Puppala Venkat
[J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2013, 28 (12) : 2490 - 2497
[2] Association of TGFb1 polymorphisms involved in radiation toxicity with TGFb1 secretion in vitro
De Ruyck, Kim
Beels, L.
van Meerbeeck, Jan P.
Deneve, Wilfried
Thierens, Hubert
[J]. JOURNAL OF THORACIC ONCOLOGY, 2009, 4 (09) : S641 - S641
[3] TGFB1 Gene Promoter Polymorphisms in Serbian Asthmatics
Dragicevic, Sandra
Petrovic-Stanojevic, Natasa
Nikolic, Aleksandra
[J]. ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, 2016, 25 (02): : 273 - 278
[4] TGFB1 gene polymorphisms and inflammatory bowel disease
García-González, MA
Crusius, JBA
Strunk, MHP
Bouma, G
Pérez-Centeno, CM
Pals, G
Meuwissen, SGM
Peña, AS
[J]. IMMUNOGENETICS, 2000, 51 (10) : 869 - 872
[5] Contribution of the TGFB1 Gene to Myocardial Infarction Susceptibility
Barsova, R. M.
Titov, B. V.
Matveeva, N. A.
Favorov, A. V.
Sukhinina, T. S.
Shahnovich, R. M.
Ruda, M. Ia.
Favorova, O. O.
[J]. ACTA NATURAE, 2012, 4 (02): : 74 - 79
[6] TGFB1 gene polymorphisms and inflammatory bowel disease
M. Asunción García-González
J. Bart A. Crusius
Mark H.P. Strunk
Gerd Bouma
Cecilia M. Pérez-Centeno
Gerard Pals
Stefan G.M. Meuwissen
A. Salvador Peña
[J]. Immunogenetics, 2000, 51 : 869 - 872
[7] TGFB1 stimulates the proliferation of quiescent oogonial stem cells in chicken
Zhang, Yun
Wu, Wenhui
Ma, Yuxiao
Wang, Xuzhao
Wei, Jiahui
Guo, Xiaotong
Xue, Man
Ji, Jiarong
Zhu, Guiyu
[J]. REPRODUCTION, 2024, 168 (01)
[8] The essential roles of TGFB1 in reproduction
Ingman, Wendy V.
Robertson, Sarah A.
[J]. CYTOKINE & GROWTH FACTOR REVIEWS, 2009, 20 (03) : 233 - 239
[9] TGFB1 gene single nucleotide polymorphisms in allergic asthma
Wisniewski, A
Obojski, A
Pawlik, A
Jasek, M
Luszczek, W
Kusnierczyk, P
[J]. TISSUE ANTIGENS, 2004, 64 (04): : 419 - 419
[10] Association of TGFB1 and IL4RnG2 gene polymorphisms with asthma
Romero Palacios, Pedro J.
Alavrez Merino, Juan Carlos
Cisneros Serrano, Carolina
De Diego Fernandez, Pablo
Gonzalez Barcala, Francisco J.
Ignacio Garcia, Jose Maria
Pereira Vega, Antonio
Perez de LLano, Luis
Urrutia Landa, Isabel
[J]. EUROPEAN RESPIRATORY JOURNAL, 2012, 40

← 1 2 3 4 5 →