Three-dimensional electrospun nanofibrous scaffolds for bone tissue engineering

被引:97
|
作者
Lin, Weimin [1 ,2 ,3 ]
Chen, Miao [1 ,2 ]
Qu, Tao [1 ,2 ]
Li, Jidong [4 ]
Man, Yi [1 ,2 ,3 ]
机构
[1] Sichuan Univ, West China Hosp Stomatol, State Key Lab Oral Dis, Chengdu, Sichuan, Peoples R China
[2] Sichuan Univ, West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis, Chengdu, Sichuan, Peoples R China
[3] Sichuan Univ, West China Hosp Stomatol, Dept Oral Implantol, Chengdu, Sichuan, Peoples R China
[4] Sichuan Univ, Res Ctr Nanobiomat, Analyt & Testing Ctr, Chengdu, Sichuan, Peoples R China
基金
中国国家自然科学基金;
关键词
3D scaffold; bone tissue engineering; electrospun; nanofiber; SILK FIBROIN SCAFFOLDS; IN-VITRO; HIERARCHICAL SCAFFOLDS; CELL INFILTRATION; HYBRID SCAFFOLDS; STEM-CELLS; FABRICATION; COMPOSITE; FIBER; SUPERABSORBENT;
D O I
10.1002/jbm.b.34479
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Electrospinning technology has been widely used in the past few decades to prepare nanofibrous scaffolds that mimic extracellular matrices. However, traditional two-dimensional (2D) electrospun nanofibrous mats still have some inherent disadvantages for bone tissue engineering, such as limited cell infiltration and lack of three-dimensional (3D) structure. The development of 3D electrospun scaffolds with larger pore sizes and porosity provides new perspectives for electrospinning-based tissue engineering scaffolds. However, there are still some challenges and areas for improvement. In this review, the applications of 3D electrospun nanofibrous scaffolds in the field of bone tissue engineering from its fabrication methods to bio-functionalization are summarized, with the aim of providing new insights into the design of electrospinning-based bone tissue engineering scaffolds.
引用
收藏
页码:1311 / 1321
页数:11
相关论文
共 50 条
  • [1] Electrospun three-dimensional aligned nanofibrous scaffolds for tissue engineering
    Jin, Guorui
    He, Rongyan
    Sha, Baoyong
    Li, Wenfang
    Qing, Huaibin
    Teng, Rui
    Xu, Feng
    [J]. MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2018, 92 : 995 - 1005
  • [2] Fabrication and characterization of three-dimensional electrospun scaffolds for bone tissue engineering
    Andric, Tea
    Wright, Lee D.
    Taylor, Brittany L.
    Freeman, Joseph W.
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2012, 100A (08) : 2097 - 2105
  • [3] Fabrication and Characterization of Three-Dimensional Electrospun Scaffolds for Bone Tissue Engineering
    Andric T.
    Taylor B.L.
    Whittington A.R.
    Freeman J.W.
    [J]. Regenerative Engineering and Translational Medicine, 2015, 1 (1-4) : 32 - 41
  • [4] Three-Dimensional Scaffolds for Bone Tissue Engineering
    Chinnasami, Harish
    Dey, Mohan Kumar
    Devireddy, Ram
    [J]. BIOENGINEERING-BASEL, 2023, 10 (07):
  • [5] Electrospun three-dimensional hyaluronic acid nanofibrous scaffolds
    Ji, Y
    Ghosh, K
    Shu, XZ
    Li, BQ
    Sokolov, JC
    Prestwich, GD
    Clark, RAF
    Rafailovich, MH
    [J]. BIOMATERIALS, 2006, 27 (20) : 3782 - 3792
  • [6] Electrospun multicomponent and multifunctional nanofibrous bone tissue engineering scaffolds
    Wang, Chong
    Wang, Min
    [J]. JOURNAL OF MATERIALS CHEMISTRY B, 2017, 5 (07) : 1388 - 1399
  • [7] Membrane-reinforced three-dimensional electrospun silk fibroin scaffolds for bone tissue engineering
    Yang, Sung Yeun
    Hwang, Tae Heon
    Che, Lihua
    Oh, Jin Soo
    Ha, Yoon
    Ryu, WonHyoung
    [J]. BIOMEDICAL MATERIALS, 2015, 10 (03)
  • [8] Recent Advancements on Three-Dimensional Electrospun Nanofiber Scaffolds for Tissue Engineering
    Yujie Chen
    Xutao Dong
    Muhammad Shafiq
    Gregory Myles
    Norbert Radacsi
    Xiumei Mo
    [J]. Advanced Fiber Materials, 2022, 4 : 959 - 986
  • [9] Recent Advancements on Three-Dimensional Electrospun Nanofiber Scaffolds for Tissue Engineering
    Chen, Yujie
    Dong, Xutao
    Shafiq, Muhammad
    Myles, Gregory
    Radacsi, Norbert
    Mo, Xiumei
    [J]. ADVANCED FIBER MATERIALS, 2022, 4 (05) : 959 - 986
  • [10] Bioceramics/Electrospun Polymeric Nanofibrous and Carbon Nanofibrous Scaffolds for Bone Tissue Engineering Applications
    Dibazar, Zahra Ebrahimvand
    Nie, Lei
    Azizi, Mehdi
    Nekounam, Houra
    Hamidi, Masoud
    Shavandi, Amin
    Izadi, Zhila
    Delattre, Cedric
    [J]. MATERIALS, 2023, 16 (07)