Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity

被引：5
|
作者：
Patel, Naiya B. [1 ]
Ostilla, Lorena A. [1 ]
Cuervo-Pardo, Lyda [2 ]
Berdnikovs, Sergejs [1 ]
Chiarella, Sergio E. [1 ]
机构：
[1] Northwestern Univ, Feinberg Sch Med, 211 East Ontario St,Suite 1000, Chicago, IL 60611 USA
[2] Univ Florida, Gainesville, FL USA
来源：
CLINICAL AND TRANSLATIONAL ALLERGY | 2019年 / 9卷 / 01期
关键词：
Asthma; Airway epithelium; Inflammation; Microarray; RELEASE;
D O I：
10.1186/s13601-019-0280-9
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
In two independent microarray studies involving primary airway epithelial cells, the relative gene expression of TMEM178 decreases with the progression of asthma severity. Our manuscript creates a paradigm for future studies dissecting the role of Tmem178 in the pathogenesis of severe asthma.
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页数：3
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