The aim of this study was to investigate the association between preoperative sagittal spinopelvic alignment and postoperative clinical outcomes after total hip arthroplasty (THA). This retrospective study included 92 patients with hip osteoarthritis who underwent primary THA between May 2013 and October 2015. Patients' characteristics, radiographic sagittal spinopelvic parameters and modified Harris Hip Scores, including function scores (gait scores and functional activities scores), were investigated. Multivariate linear regression analysis was performed to determine the associations between each preoperative sagittal spinopelvic parameter and postoperative hip function The preoperative sagittal spinopelvic parameters that were associated with postoperative gait scores were sagittal vertical axis (adjusted beta-coefficient= 0.28, P = 0.02), lumbar lordosis angle (adjusted beta-coefficient 0.29, P = 0.0089), pelvic tilt (adjusted beta-coefficient= 0.25, P= 0.045), sacral slope (adjusted beta-coefficient= 0.27, P= 0.017) and pelvic incidence minus lumbar lordosis angle (adjusted beta-coefficient = 0.31, P=0.01). The preoperative sagittal spinopelvic parameters that were related to the postoperative functional activities scores were sagittal vertical axis (adjusted beta-coefficient 0.38, P= 0.0051) and pelvic incidence minus lumbar lordosis angle (adjusted beta-coefficient = 0.39, P= 0.0033). Patients with preoperative imbalanced sagittal alignment such as larger sagittal vertical axis, larger pelvic incidence minus lumbar lordosis and retroversion of pelvis had poorer clinical outcomes than others after THA. While, those preoperative imbalanced patients with anteversion of pelvis may have a compensatory ability which could correct the abnormal sagittal alignment after THA. Preoperative sagittal spinopelvic alignment affected postoperative clinical outcomes after THA. (C) 2016 Elsevier B.V. All rights reserved.