Preparation of nitriles from primary amides under swern oxidation conditions

被引：54
|
作者：
Nakajima, N
Ubukata, M
机构：
[1] Biotechnology Research Center, Toyama Prefectural University, Kosugi
来源：
TETRAHEDRON LETTERS | 1997年 / 38卷 / 12期
关键词：
D O I：
10.1016/S0040-4039(97)00316-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In order to establish a mild conversion method of primary amides to nitriles, various types of carboxamides were treated under Swem oxidation conditions, (COCl)(2)DMSO and Et(3)N, as a dehydrating agent to obtain desired nitriles in 75-96% yields. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：2099 / 2102
页数：4
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