Natural products-based insecticidal agents 20. Design, synthesis and insecticidal activity of novel honokiol/magnolol azo derivatives

被引:17
|
作者
Yang, Chun [1 ]
Zhi, Xiaoyan [1 ]
Li, Jie [1 ]
Zha, Jing [1 ]
Xu, Hui [1 ,2 ]
机构
[1] Northwest A&F Univ, Res Inst Pesticidal Design & Synth, Coll Sci, Yangling 712100, Shaanxi, Peoples R China
[2] Northwest A&F Univ, Coll Plant Protect, Yangling 712100, Shaanxi, Peoples R China
基金
中国国家自然科学基金;
关键词
Honokiol; Magnolol; Insecticidal activity; Natural-product-based insecticide; Structural modification; Mythimna separata walker; CROSS-RESISTANCE; ESSENTIAL OIL; LEPIDOPTERA; HONOKIOL; APOPTOSIS; ARMYWORM; MAGNOLOL;
D O I
10.1016/j.indcrop.2015.08.003
中图分类号
S2 [农业工程];
学科分类号
0828 ;
摘要
Honokiol and magnolol are small-molecule polyphenols isolated from the barks of Magnolia officinalis. To discover novel natural-product-based pesticidal agents, a series of honokiol/magnolol azo derivatives were prepared by structural modification of honokiol or magnolol. Their insecticidal activity was evaluated at 1 mg/mL against the pre-third-instar larvae of oriental armyworm (Mythimna separata Walker), a typical lepidopteran pest. Among all derivatives, 5m and 6k exhibited more promising insecticidal activity with the final mortality rates greater than 60%, when compared with their precursors (honokiol and magnolol) and the positive control, toosendanin. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:761 / 767
页数:7
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