Triple-site pacing for cardiac resynchronization in permanent atrial fibrillation: follow-up results from a prospective observational study

被引:0
|
作者
Marques, Pedro [1 ]
Menezes, Miguel Nobre [1 ]
da Silva, Gustavo Lima [1 ]
Guimaraes, Tatiana [1 ]
Bernardes, Ana [1 ]
Cortez-Dias, Nuno [1 ]
Carpinteiro, Luis [1 ]
de Sousa, Joao [1 ]
Pinto, Fausto J. [1 ]
机构
[1] Univ Lisbon, Cardiovasc Ctr, Lisbon Acad Med Ctr, Santa Maria Univ Hosp CHLN,Cardiol Dept,Fac Med, Av Prof Egas Moniz, P-1649035 Lisbon, Portugal
来源
EUROPACE | 2018年 / 20卷 / 06期
关键词
Cardiac resynchronization therapy; Multi-site pacing; Triple-site pacing; Heart failure; Atrial fibrillation; Cardiac output; QRS duration; Ejection fraction; Responder; Super-responder; CONGESTIVE-HEART-FAILURE; VENTRICULAR STIMULATION; THERAPY; FEASIBILITY; TRIAL;
D O I
10.1093/europace/eux036
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims Cardiac Resynchronization Therapy (CRT) is associated with a particularly high non-response rate in patients with atrial fibrillation (AF). We aimed to assess the effectiveness of triple-site (Tri-V) pacing CRT in this population. Methods and results Prospective observational study of patients with permanent AF who underwent CRT implantation with an additional right ventricle lead in the outflow tract septal wall. After implantation, programming mode (Tri-V or biven-tricular pacing) was selected based on cardiac output determination. Patients were classified as responders if NYHA class was reduced by at least one level and echocardiographic ejection fraction (EF) increased >= 10%, and as super-responders if in NYHA class I and EF >= 50%. Forty patients (93% male, mean age 72 +/- 10 years) were included. Thirty-three were programmed in Tri-V. The following results pertain to this subgroup. At baseline, 58% were in NYHA class III and 36% NYHA class II. At 1 year follow-up, Minnesota QoL score was reduced (36 +/- 23 vs. 8 +/- 6; P = 0.001) and the 6MWT distance improved (384 +/- 120 m to 462 +/- 87 m, P = 0.003). Mean EF increased (26% +/- 8 vs. 39 +/- 10; P < 0.001 at 6 months and 41 +/- 10; P < 0.001 at 12 months). Responder rate was 59% at 6 months and 79% at 12 months. Super-responder rate was 9% at 6 months and 16% at 12 months. One year survival free from heart failure hospitalization was 87.9%. Conclusion Tri-V CRT yielded higher response and super-response rates than usually reported for CRT in patients with permanent AF using clinical and remodeling criteria.
引用
收藏
页码:986 / 992
页数:7
相关论文
共 50 条
  • [1] Triple-site pacing for cardiac resynchronization in permanent atrial fibrillation - Acute phase results from a prospective observational study
    Marques, Pedro
    Menezes, Miguel Nobre
    da Silva, Gustavo Lima
    Bernardes, Ana
    Magalhaes, Andreia
    Cortez-Dias, Nuno
    Carpinteiro, Luis
    de Sousa, Joao
    Pinto, Fausto J.
    [J]. REVISTA PORTUGUESA DE CARDIOLOGIA, 2016, 35 (06) : 331 - 338
  • [2] Triple-site pacing cardiac resynchronization therapy in patients with permanent atrial fibrillation: results from a prospective observational study
    Guimaraes, T.
    Marques, P.
    Menezes, M. N.
    Lima Da Silva, G.
    Bernardes, A.
    Francisco, A. R. G.
    Goncalves, I.
    Agostinho, J. R.
    Cortez-Dias, N.
    Carpinteiro, L.
    De Sousa, J.
    Pinto, F. J.
    [J]. EUROPEAN HEART JOURNAL, 2016, 37 : 641 - 642
  • [3] Triple-site pacing for cardiac resynchronization in atrial fibrillation - an opening onto different scenarios
    Oliveira, Mario
    [J]. REVISTA PORTUGUESA DE CARDIOLOGIA, 2016, 35 (06) : 339 - 341
  • [4] Are acute phase QRS and cardiac output measurements good predictors of triple-site pacing cardiac resynchronization therapy in permanent atrial fibrillation?
    Lima Da Silva, G.
    Marques, P.
    Nobre Menezes, M.
    Guimaraes, T.
    Francisco, A. R. G.
    Agostinho, J.
    Goncalves, I.
    Bernardes, A.
    Cortez-Dias, N.
    Carpinteiro, L.
    De Sousa, J.
    Pinto, F. J.
    [J]. EUROPEAN HEART JOURNAL, 2016, 37 : 1288 - 1288
  • [5] Can linear triple-site atrial pacing reinforce the electrical treatment of atrial fibrillation?
    van Hemel, Norbert
    [J]. EUROPACE, 2010, 12 (04): : 458 - 459
  • [6] Triple-site pacing in patients with biventricular device - Incidence of the phenomenon and cardiac resynchronization benefit
    Bulava, A
    Ansalone, G
    Ricci, R
    Giannantoni, P
    Pignalberi, C
    Heinc, P
    Lukl, J
    Santini, M
    [J]. JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, 2004, 10 (01) : 37 - 45
  • [7] Triple-Site Pacing in Patients with Biventricular Device—Incidence of the Phenomenon and Cardiac Resynchronization Benefit
    Alan Bulava
    Gerardo Ansalone
    Renato Ricci
    Paride Giannantoni
    Carlo Pignalberi
    Petr Heinc
    Jan Lukl
    Massimo Santini
    [J]. Journal of Interventional Cardiac Electrophysiology, 2004, 10 : 37 - 45
  • [8] Triple-site cardiac resynchronization therapy in patients with heart failure - the prospective, randomized trial
    Lenarczyk, R.
    Kowalski, O.
    Sredniawa, B.
    Pruszkowska-Skrzep, P.
    Pluta, S.
    Sokal, A.
    Szulik, M.
    Kukulski, T.
    Zielinska, T.
    Kalarus, Z.
    [J]. EUROPEAN HEART JOURNAL, 2011, 32 : 145 - 145
  • [9] Cardiac resynchronization therapy in patients with atrial fibrillation: a 3-year follow-up study
    Tsuboi, R.
    [J]. EUROPEAN JOURNAL OF HEART FAILURE, 2014, 16 : 32 - 32
  • [10] Atrial fibrillation at follow-up does not worsen the prognosis of cardiac resynchronization therapy
    Belen Alvarez, B.
    Garcia Seara, F. J.
    Iglesias Alvarez, D.
    Abellas Sequeiros, R. A.
    Gonzalez Melchor, L.
    Rodriguez Manero, M.
    Fernandez Lopez, X. A.
    Martinez Monzonis, A.
    Varela Roman, A.
    Martinez Sande, J. L.
    Gonzalez Juanatey, J. R.
    [J]. EUROPEAN JOURNAL OF HEART FAILURE, 2017, 19 : 280 - 280