Decision Making in Indeterminate Thyroid Nodules and the Role of Molecular Testing

被引：9

作者：

Mitchell, Janeil ^{[1
]}

Yip, Linwah ^{[2
]}

机构：

[1] Fox Valley Surg Associates, Endocrine Surg, 1818 North Meade St, Appleton, WI 54911 USA

[2] Univ Pittsburgh, Sch Med, Dept Surg, Div Endocrine Surg, Kaufman Med Bldg,3471 Fifth Ave,Suite 101, Pittsburgh, PA 15213 USA

来源：

SURGICAL CLINICS OF NORTH AMERICA | 2019年 / 99卷 / 04期

关键词：

Indeterminate thyroid nodule; Gene mutations; Molecular testing; Mutational analysis; Gene expression classifier; Gene sequencing; microRNA classifier; TERT PROMOTER MUTATIONS; GENE-EXPRESSION CLASSIFIER; BRAF V600E MUTATION; ENCAPSULATED FOLLICULAR VARIANT; COST-EFFECTIVENESS; BETHESDA SYSTEM; RET/PTC REARRANGEMENTS; PREOPERATIVE DIAGNOSIS; NUCLEAR FEATURES; MAJOR INDICATOR;

D O I：

10.1016/j.suc.2019.04.002

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Cytologically indeterminate thyroid nodules are associated with a broad range (5%-75%) of malignant risk and accurately informing definitive management poses a challenge. Advancements in molecular testing of fine-needle aspiration biopsies have improved preoperative diagnostic accuracy and prognostication. For indeterminate nodules, such testing ideally will reduce the need for surgery for benign nodules and potentially guide appropriate extent of initial surgery for malignancy.

引用

页码：587 / +

页数：13

共 50 条

[1] Molecular testing in indeterminate thyroid nodules: an additional tool for clinical decision-making
Fumagalli, Caterina
Serio, Giovanni
[J]. PATHOLOGICA, 2023, 115 (04) : 205 - 216
[2] How Effective is the Use of Molecular Testing in Preoperative Decision Making for Management of Indeterminate Thyroid Nodules?
David Steinmetz
Mary Kim
Jee-Hye Choi
Tamanie Yeager
Krupa Samuel
Nazanin Khajoueinejad
Alison Buseck
Sayed Imtiaz
Gustavo Fernandez-Ranvier
Denise Lee
Randall Owen
Aida Taye
[J]. World Journal of Surgery, 2022, 46 : 3043 - 3050
[3] How Effective is the Use of Molecular Testing in Preoperative Decision Making for Management of Indeterminate Thyroid Nodules?
Steinmetz, David
Kim, Mary
Choi, Jee-Hye
Yeager, Tamanie
Samuel, Krupa
Khajoueinejad, Nazanin
Buseck, Alison
Imtiaz, Sayed
Fernandez-Ranvier, Gustavo
Lee, Denise
Owen, Randall
Taye, Aida
[J]. WORLD JOURNAL OF SURGERY, 2022, 46 (12) : 3043 - 3050
[4] Role of Dynamic Markers in the Molecular Testing of Indeterminate Thyroid Nodules
Banizs, Anna B.
Toney, Nicole A.
Jackson, Sara A.
Narick, Christina M.
Silverman, Jan E.
Finkelstein, Sydney D.
[J]. AJSP-REVIEWS AND REPORTS, 2019, 24 (01): : 9 - 12
[5] Ancillary Molecular Testing of Indeterminate Thyroid Nodules
Rossi, Esther Diana
Larocca, Luigi Maria
Pantanowitz, Liron
[J]. CANCER CYTOPATHOLOGY, 2018, 126 : 654 - 671
[6] Authors’ Reply: How Effective is the Use of Molecular Testing in Preoperative Decision Making for Management of Indeterminate Thyroid Nodules
David Steinmetz
Aida Taye
[J]. World Journal of Surgery, 2023, 47 : 1584 - 1584
[7] Authors' Reply: How Effective is the Use of Molecular Testing in Preoperative Decision Making for Management of Indeterminate Thyroid Nodules
Steinmetz, David
Taye, Aida
[J]. WORLD JOURNAL OF SURGERY, 2023, 47 (06) : 1584 - 1584
[8] Indeterminate Thyroid Nodules: From Cytology to Molecular Testing
Vignali, Paola
Macerola, Elisabetta
Poma, Anello Marcello
Sparavelli, Rebecca
Basolo, Fulvio
[J]. DIAGNOSTICS, 2023, 13 (18)
[9] Update on Molecular Testing for Cytologically Indeterminate Thyroid Nodules
Bose, Shikha
Sacks, Wendy
Walts, Ann E.
[J]. ADVANCES IN ANATOMIC PATHOLOGY, 2019, 26 (02) : 114 - 123
[10] Update on Molecular Testing for Cytologically Indeterminate Thyroid Nodules
Nishino, Michiya
Nikiforova, Marina
[J]. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 2018, 142 (04) : 446 - 457

← 1 2 3 4 5 →