Anterior-posterior polarity in C-elegans and Drosophila -: PARallels and differences

被引：104
|
作者：
Pellettieri, J [1 ]
Seydoux, G [1 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Dept Mol Biol & Genet, Baltimore, MD 21205 USA
来源：
SCIENCE | 2002年 / 298卷 / 5600期
关键词：
D O I：
10.1126/science.1072162
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The eggs of Caenorhabditis elegans and Drosophila bear little similarity to each other, yet both depend on the par genes for control of anterior-posterior polarity. Here we explore possible common roles for the par genes (pars) in converting transient asymmetries into stably polarized axes. Although clear mechanistic parallels remain to be established, par-dependent regulation of microtubule dynamics and protein stability emerge as common themes.
引用
收藏
页码：1946 / 1950
页数：5
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