Synthesis of Some New Thieno[2,3-d]pyrimidine Derivatives

被引：0

作者：

Abdelrazek, Fathy M. ^{[1
]}

Mohamed, Ashraf M. ^{[2
]}

ElSayed, Akram N. ^{[1
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

[2] Natl Res Ctr, Dept Appl Organ Chem, Giza, Egypt

来源：

AFINIDAD | 2008年 / 65卷 / 536期

关键词：

Thiophene; Thieno[2,3-d]pyrimidine; Thieno[2,3-b]pyridine;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The thiophene derivative 3 reacts with formamide, phenyl isothiocyanate, benzoyl isothiocyanate, trichloroacetonitrile, malononitrile and benzoyl acetonitrile to afford the thieno[2,3-d]pyrimidine derivatives 4, 6, 7, 8, 9, 10, 13 and 18. The reaction of 3 with ethyl cyanoacetate afforded however the thieno[2,3-b]pyridine derivative 16; and with phenacyl thiocyanate led to the 2-thiazol-2-ylamino thiophene derivative 20a.

引用

页码：322 / 326

页数：5

共 50 条

[1] Synthesis and Cytotoxicity of Some Thieno[2,3-d]pyrimidine Derivatives
Saddik, Abdelreheem A.
El-Dean, Adel M. Kamal
El-Sokary, Gamal H.
Hassan, Khairy M.
Abbady, Mohamed S.
Ismail, Ismail A.
Saber, Saber H.
[J]. JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2017, 64 (01) : 87 - 93
[2] SYNTHESIS OF (2,3-D)-THIENO-PYRIMIDINE AND OF SOME DERIVATIVES
ROBBA, M
LECOMTE, JM
DESEVRIC.MC
[J]. COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE C, 1968, 266 (02): : 128 - &
[3] SYNTHESIS AND REACTIONS OF SOME THIENO[2,3-D]PYRIMIDINE DERIVATIVES
KHALIL, ZH
GEIES, AA
[J]. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1991, 60 (3-4): : 223 - 231
[4] SYNTHESIS OF NEW THIENO[2,3-D] PYRIMIDINE-DERIVATIVES
IBRAHIEM, LI
TAMMAM, GH
ABDIN, TMS
[J]. JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, 1989, 11 (03): : 227 - 231
[5] New method of thieno[2,3-d]pyrimidine derivatives synthesis
Ryabova, OB
Evstratova, ML
Makarov, VA
Tafeenko, VA
Granik, VG
[J]. KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2004, (10): : 1564 - 1571
[6] DERIVATIVES OF PYRIMIDINE .56. A NEW SYNTHESIS OF THIENO[2,3-D]PYRIMIDINE
MELIKOGANDZHANYAN, RG
GAPOYAN, AS
KHACHATRYAN, VE
MIRZOYAN, VS
[J]. KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1982, (01): : 118 - 120
[7] Synthesis of Some New Substituted Thieno[2,3-d]pyrimidine Derivatives as Antimicrobial Agents
M. F. El-Shehry
H. M. Hosni
A. E. Amr
A. A. Ibrahim
Ahmed A. Fayed
D. H. Elnaggar
[J]. Russian Journal of General Chemistry, 2019, 89 : 1528 - 1534
[8] Synthesis of Some New Substituted Thieno[2,3-d]pyrimidine Derivatives as Antimicrobial Agents
El-Shehry, M. F.
Hosni, H. M.
Amr, A. E.
Ibrahim, A. A.
Fayed, Ahmed A.
Elnaggar, D. H.
[J]. RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2019, 89 (07) : 1528 - 1534
[9] Synthesis and in vitro antitumor evaluation of some new thiophenes and thieno[2,3-d]pyrimidine derivatives
Fouad, Mahasen M.
El-Bendary, Eman R.
Suddek, Ghada M.
Shehata, Ihsan A.
El-Kerdawy, Mohamed M.
[J]. BIOORGANIC CHEMISTRY, 2018, 81 : 587 - 598
[10] Facile Syntheses of Some Thieno[2,3-d]Pyrimidine Derivatives
Aly, A. S.
Abu-Zied, Kh. M.
Gaafar, Alaa El-Din M.
[J]. PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2008, 183 (12) : 3063 - 3078

← 1 2 3 4 5 →