The problem of underdeveloped region development is written in the National RPJM document 2015-2019 which is mentioned as the management of potential local resources in the development of underdeveloped region economy. Through the processing of the resources, it is expected to alleviate poverty and increase the local economy. As the effort of realizing the development of new economic growth centers in underdeveloped regions, the government has launched a flagship program based on the development of leading commodities of district by prioritizing the development of local specific potential of underdeveloped regions overall with the result that this effort is expected to encourage and accelerate economic growth and improve the welfare of the society where it will eventually build a new center of economic growth. Generally, each district's flagship program is aimed at encouraging the eradication of regions from the lag. From the six lagging parameters which include the society's economy, human resources, infrastructure, local financial capacity (fiscal gap), accessibility, and regional characteristics, the government programs are undertaken to improve the society's economy including poverty alleviation and lower unemployment and to improve the financial local capacity through the optimization of potential local products. The development of the district's leading product program in the growth center area will provide significant benefits in promoting the economic growth of the society. The results of this study obtained shortlist of the district's leading agriculture product with LQ (Location Quotient) as big as 4.28 for peanut; 4.23 for green beans; 3.37 for soybeans; 1.64 for cassava and 0.70 for maize. In the farm sector, tobacco scores LQ as big as 3.89; 0,59 for cashew and the last 0.01 for coconut. For the livestock sector, LQ of cattle commodity is 11.9; 4.93 for goats and 2.90 for duck. From the short list data per sector, it is obtained shortlist of leading products which are cassava, tobacco, cow, goat and duck. From the FGD results and in-depth discussion, the leading product of Sampang district is cattle.