Age-moderation of genetic and environmental contributions to cognitive functioning in mid- and late-life for specific cognitive abilities

被引：12

作者：

Pahlen, Shandell ^{[1
,2
]}

Hamdi, Nayla R. ^{[1
]}

Aslan, Anna K. Dahl ^{[3
,4
]}

Horwitz, Briana N. ^{[5
]}

Panizzon, Matthew S. ^{[6
]}

Petersen, Inge ^{[7
]}

Zavala, Catalina ^{[2
,9
]}

Christensen, Kaare ^{[7
]}

Finkel, Deborah ^{[8
]}

Franz, Carol E. ^{[6
]}

Gatz, Margaret ^{[3
,9
]}

Johnson, Wendy ^{[10
]}

Kremen, William S. ^{[6
]}

Krueger, Robert F. ^{[1
]}

Neiderhiser, Jenae M. ^{[11
]}

Reynolds, Chandra A. ^{[2
]}

Pedersen, Nancy L. ^{[3
,9
]}

McGue, Matt ^{[1
,7
]}

机构：

[1] Univ Minnesota, Dept Psychol, Minneapolis, MN 55455 USA

[2] Univ Calif Riverside, Dept Psychol, 900 Univ Ave, Riverside, CA 92521 USA

[3] Karolinska Inst, Dept Med Epidemiol & Biostat, SE-17177 Stockholm, Sweden

[4] Jonkoping Univ, Jonkoping Sch Hlth & Welf, Jonkoping, Sweden

[5] Calif State Univ Fullerton, Dept Psychol, Fullerton, CA 92834 USA

[6] Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA

[7] Univ Southern Denmark, Danish Aging Res Ctr, Danish Twin Register, DK-5000 Odense C, Denmark

[8] Indiana Univ Southeast, Dept Psychol, New Albany, IN 47150 USA

[9] Univ Southern Calif, Dept Psychol, Los Angeles, CA 90089 USA

[10] Univ Edinburgh, Dept Psychol, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland

[11] Penn State Univ, Dept Psychol, University Pk, PA 16802 USA

来源：

INTELLIGENCE | 2018年 / 68卷

基金：

瑞典研究理事会; 美国国家卫生研究院;

关键词：

Aging; Behavior genetics; Cognitive ability; Adult development; INDIVIDUAL-DIFFERENCES; LONGITUDINAL TWIN; METAANALYSIS; HERITABILITY; ADOPTION; HEALTH; SPAN; OLD; ADULTHOOD; ORIGINS;

D O I：

10.1016/j.intell.2017.12.004

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

Age moderation of genetic and environmental contributions to Digits Forward, Digits Backward, Block Design, Symbol Digit, Vocabulary, and Synonyms was investigated in a sample of 14,534 twins aged 26 to 98 years. The Interplay of Genes and Environment across Multiple Studies (IGEMS) consortium contributed the sample, which represents nine studies from three countries (USA, Denmark, and Sweden). Average test performance was lower in successively older age groups for all tests. Significant age moderation of additive genetic, shared environmental, and non-shared environmental variance components was observed, but the pattern varied by test. The genetic contribution to phenotypic variance across age was smaller for both Digit Span tests, greater for Synonyms, and stable for Block Design and Symbol Digit. The non-shared environmental contribution was greater with age for the Digit Span tests and Block Design, while the shared environmental component was small for all tests, often more so with age. Vocabulary showed similar age-moderation patterns as Synonyms, but these effects were nonsignificant. Findings are discussed in the context of theories of cognitive aging.

引用

页码：70 / 81

页数：12

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