Lynch Syndrome and Endometrial Cancer

被引：14
|
作者：
Singh, Sareena [1 ]
Resnick, Kimberly E. [1 ]
机构：
[1] Metrohlth Med Ctr, Div Gynecol Oncol, Dept OB GYN, Canc Care Pavil,2500 MetroHlth Dr, Cleveland, OH 44109 USA
来源：
SOUTHERN MEDICAL JOURNAL | 2017年 / 110卷 / 04期
关键词：
endometrial cancer; genetics; gynecology; Lynch syndrome; risk reduction; NONPOLYPOSIS COLORECTAL-CANCER; MISMATCH-REPAIR GENES; CA; 125; BETHESDA GUIDELINES; GYNECOLOGIC CANCER; GERMLINE MUTATIONS; RISK; PREDICTION; HNPCC; WOMEN;
D O I：
10.14423/SMJ.0000000000000633
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In patients with Lynch syndrome, gynecologic cancer often can be the first presenting malignancy. In this review, we summarize the genetics of Lynch syndrome and review the various modalities of identifying patients at risk for this syndrome. The clinical characteristics of Lynch-associated endometrial cancer and screening and risk-reducing strategies also are described.
引用
收藏
页码：265 / 269
页数：5
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