Imaging Brain SV2A Density Measured With [11 C]UCB-J μPET as a Readout Of Depression and Antidepressant Response in a Mouse Model of Depression

被引：0
|
作者：
Leroy, Claire [1 ]
Goutal, Sebastien [1 ]
David, Denis [1 ]
Saba, Wadad [1 ]
Goislard, Maud [1 ]
Bottlaender, Michel [1 ]
Caille, Fabien [1 ]
Nguyen, Phi T. [1 ]
Gardier, Alain [1 ]
Hen, Rene [1 ]
Corruble, Emmanuelle [1 ]
Colle, Romain [1 ]
Tournier, Nicolas [1 ]
Mendez-David, Indira [1 ]
机构：
[1] Univ Paris Saclay, Ctr Rech Epidemiol & Sante Populat CESP, INSERM, UMR 1018,UVSQ, Orsay, France
来源：
NEUROPSYCHOPHARMACOLOGY | 2022年 / 47卷
关键词：
Synaptogenesis; Biomarker; Positron Emission; Tomography (PET); Depression; Antidepressant;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
P327
引用
收藏
页码：252 / 253
页数：2
相关论文
共 50 条
  • [1] Imaging Brain SV2A Density Measured With [11 C]UCB-J mu PET as a Readout Of Depression and Antidepressant Response in a Mouse Model of Depression
    Leroy, Claire
    Goutal, Sebastien
    David, Denis
    Saba, Wadad
    Goislard, Maud
    Bottlaender, Michel
    Caille, Fabien
    Nguyen, Phi T.
    Gardier, Alain
    Hen, Rene
    Corruble, Emmanuelle
    Colle, Romain
    Tournier, Nicolas
    Mendez-David, Indira
    NEUROPSYCHOPHARMACOLOGY, 2022, 47 (SUPPL 1) : 252 - 253
  • [2] Evaluation of synaptic density using SV2A PET imaging as a readout of depression and antidepressant response in a mice model of depression
    Leroy, C.
    Goutal, S.
    Mendez-David, I.
    Saba, W.
    Goislard, M.
    Bottlaender, M.
    Caille, F.
    Gardier, A.
    Corruble, E.
    Lebon, V.
    Colle, R.
    Tournier, N.
    David, D.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022, 49 (SUPPL 1) : S185 - S186
  • [3] [11C]UCB-J PET imaging of synaptic vesicle protein SV2A in cognitive decline
    DiFilippo, Alexandra
    Tullis, Tyler
    Zammit, Matthew
    Murali, Dhanabalan
    McKinney, Grace
    Davenport, Nancy
    Barnhart, Todd
    Betthauser, Tobey
    Engle, Jonathan
    Stone, Charles
    Johnson, Sterling
    Bendlin, Barbara
    Christian, Bradley
    JOURNAL OF NUCLEAR MEDICINE, 2020, 61
  • [4] [11C]UCB-J: A novel PET tracer for imaging the synaptic vesicle glycoprotein 2A (SV2A)
    Nabulsi, Nabeel
    Hannestad, Jonas
    Holden, Daniel
    Mercier, Joel
    Najafzadeh, Soheila
    Lin, Shu-fei
    Labaree, David
    Laruelle, Marc
    Carson, Richard
    Huang, Yiyun
    JOURNAL OF NUCLEAR MEDICINE, 2014, 55
  • [5] In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET
    Thomsen, Majken B.
    Jacobsen, Jan
    Lillethorup, Thea P.
    Schacht, Anna C.
    Simonsen, Mette
    Romero-Ramos, Marina
    Brooks, David J.
    Landau, Anne M.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2021, 41 (04): : 819 - 830
  • [6] EVALUATION OF [11C]UCB-J AS A NOVEL PET RADIOLIGAND FOR IMAGING SYNAPTIC VESICLE GLYCOPROTEIN 2A (SV2A) IN THE HUMAN BRAIN
    Finnema, S. J.
    Nabulsi, N.
    Mercier, J.
    Lin, S.
    Najafzadeh, S.
    Ropchan, J.
    Hannestad, J.
    Eid, T.
    Detyniecki, K.
    Carson, R. E.
    Huang, Y.
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2016, 36 : 133 - 134
  • [7] Improved synthesis of SV2A targeting radiotracer [11C]UCB-J
    Johanna Rokka
    Eva Schlein
    Jonas Eriksson
    EJNMMI Radiopharmacy and Chemistry, 4
  • [8] Quantifying SV2A density and drug occupancy in the human brain using [11C]UCB-J PET imaging and subcortical white matter as reference tissue
    Koole, Michel
    van Aalst, June
    Devrome, Martijn
    Mertens, Nathalie
    Serdons, Kim
    Lacroix, Brigitte
    Mercier, Joel
    Sciberras, David
    Maguire, Paul
    Van Laere, Koen
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2019, 46 (02) : 396 - 406
  • [9] [11C]UCB-J is a suitable PET tracer for imaging of synaptic vesicle glycoprotein 2A (SV2A) in human
    Finnema, Sjoerd
    Nabulsi, Nabeel
    Mercier, Joel
    Lin, Shu-fei
    Najafzadeh, Soheila
    Ropchan, Jim
    Hannestad, Jonas
    Carson, Richard
    Huang, Yiyun
    JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (03)
  • [10] Quantifying SV2A density and drug occupancy in the human brain using [11C]UCB-J PET imaging and subcortical white matter as reference tissue
    Michel Koole
    June van Aalst
    Martijn Devrome
    Nathalie Mertens
    Kim Serdons
    Brigitte Lacroix
    Joel Mercier
    David Sciberras
    Paul Maguire
    Koen Van Laere
    European Journal of Nuclear Medicine and Molecular Imaging, 2019, 46 : 396 - 406
12345