Rational Optimization of the Petasis Three-Component Reaction as a Feasible Elementary Reaction in Polymer Chemistry

被引：2
|
作者：
Takahashi, Ryo [1 ]
Kakuchi, Ryohei [1 ]
机构：
[1] Gunma Univ, Div Mol Sci, Fac Sci & Technol, 1-5-1 Tenjin, Kiryu, Gunma 3768515, Japan
来源：
MACROMOLECULAR CHEMISTRY AND PHYSICS | 2021年 / 222卷 / 02期
关键词：
α ‐ amino acids; multicomponent reactions; Petasis reaction; AMINO; POLYPEPTIDE; COPOLYMERS;
D O I：
10.1002/macp.202000347
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
In this research, the Petasis three-component reaction (Petasis-3CR) among aromatic boronic acids, amines, and glyoxylic acids is feasibly optimized to seek integration with polymer synthesis. The Petasis-3CR is expanded using protected boronic acids, bypassing the disadvantages of the polymers featuring boronic acids. Based on the modification, the Petasis-3CR is now highly compatible with synthetic polymer chemistry, yielding poly (alpha-amino acids), which are otherwise difficult to synthesize.
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页数：6
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