Oocyte Competence in Women with Polycystic Ovary Syndrome

被引：160
|
作者：
Palomba, Stefano [1 ]
Daolio, Jessica [1 ]
La Sala, Giovanni Battista [1 ,2 ]
机构：
[1] IRCCS Arcispedale Santa Maria Nuova, Unit Gynecol & Obstet, Viale Risorgimento 80, I-42123 Reggio Emilia, Italy
[2] Univ Modena & Reggio Emilia, Via Univ 4, I-41100 Modena, Italy
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2017年 / 28卷 / 03期
关键词：
IN-VITRO FERTILIZATION; ANTI-MULLERIAN HORMONE; INTRACYTOPLASMIC SPERM INJECTION; CUMULUS CELLS; FOLLICULAR-FLUID; VITAMIN-D; REPRODUCTIVE OUTCOMES; PREGNANCY COMPLICATIONS; PREDICTIVE-VALUE; GENE-EXPRESSION;
D O I：
10.1016/j.tem.2016.11.008
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age and affects fertility and pregnancy in cases of oligoanovulation. Ovulation induction is often used to treat anovulatory patients with PCOS, but many of these women fail to conceive and resort to assisted reproductive technologies. Alterations in oocyte competence (OC) are considered potential causative factors for subfertility in women with PCOS. In this review we present and critically assess all recent clinical and experimental data regarding OC in women with PCOS. Our analysis demonstrates that the contribution of OC to reproductive potential in women with PCOS varies and largely depends on the PCOS phenotype and comorbidities associated with PCOS.
引用
收藏
页码：186 / 198
页数：13
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