Genetic polymorphisms and traumatic brain injury: the contribution of individual differences to recovery

被引：22
|
作者：
Weaver, Starla M. [1 ]
Portelli, Jaclyn N. [1 ]
Chau, Aileen [1 ]
Cristofori, Irene [1 ]
Moretti, Laura [1 ]
Grafman, Jordan [1 ]
机构：
[1] Kessler Fdn Res Ctr, Traumat Brain Injury Res Lab, W Orange, NJ 07052 USA
来源：
BRAIN IMAGING AND BEHAVIOR | 2014年 / 8卷 / 03期
关键词：
Genetic polymorphisms; Traumatic brain injury; Polymorphisms; APOLIPOPROTEIN-E GENOTYPE; O-METHYLTRANSFERASE GENE; COMT VAL(108/158) MET; ANGER-RELATED TRAITS; WORKING-MEMORY; DECISION-MAKING; EXECUTIVE FUNCTION; PREFRONTAL CORTEX; MONOAMINE-OXIDASE; RECEPTOR GENE;
D O I：
10.1007/s11682-012-9197-9
中图分类号：
R445 [影像诊断学];
学科分类号：
100207 ;
摘要：
Recovery after Traumatic Brain Injury (TBI) is variable, even for patients with similar severity of brain injury. Recent research has highlighted the contribution that genetic predisposition plays in determining TBI outcome. This review considers the potential for genetic polymorphisms to influence recovery of cognitive and social processes following TBI. Limitations and considerations that researchers should make when assessing the potential impact of polymorphisms on TBI outcome are also discussed. Understanding the genetic factors that support neuroplasticity will contribute to an understanding of the variation in outcome following injury and help to identify potential targets for rehabilitation.
引用
收藏
页码：420 / 434
页数：15
相关论文
共 50 条
  • [1] Genetic polymorphisms and traumatic brain injury: the contribution of individual differences to recovery
    Starla M. Weaver
    Jaclyn N. Portelli
    Aileen Chau
    Irene Cristofori
    Laura Moretti
    Jordan Grafman
    [J]. Brain Imaging and Behavior, 2014, 8 : 420 - 434
  • [2] Genetic Polymorphisms Influence Recovery from Traumatic Brain Injury
    Weaver, Starla M.
    Chau, Aileen
    Portelli, Jaclyn N.
    Grafman, Jordan
    [J]. NEUROSCIENTIST, 2012, 18 (06): : 631 - 644
  • [3] Neurobiological Influences on Recovery from Traumatic Brain Injury: The Role of Genetic Polymorphisms
    Weaver, Starla M.
    Portelli, Jaclyn N.
    [J]. CURRENT PHARMACEUTICAL DESIGN, 2014, 20 (26) : 4275 - 4283
  • [4] The genetic basis of inter-individual variation in recovery from traumatic brain injury
    Daniel Cortes
    Martin F. Pera
    [J]. npj Regenerative Medicine, 6
  • [5] The genetic basis of inter-individual variation in recovery from traumatic brain injury
    Cortes, Daniel
    Pera, Martin F.
    [J]. NPJ REGENERATIVE MEDICINE, 2021, 6 (01)
  • [6] Procedural Memory Following Traumatic Brain Injury: The Role of Individual Differences
    Rigon, Arianna
    Klooster, Nathaniel
    Crooks, Samantha
    Duff, Melissa
    [J]. BRAIN INJURY, 2019, 33 : 142 - 143
  • [7] Contribution of factor VII polymorphisms to coagulopathy in patients with isolated traumatic brain injury
    Fang, Jiang
    Yuan, Qiang
    Du, Zhuoying
    Liu, Chaobo
    Xu, Hao
    Yang, Weijian
    Chen, Long
    Zhao, Jianlan
    Xie, Rong
    Hu, Jin
    Wu, Xing
    [J]. CLINICAL NEUROLOGY AND NEUROSURGERY, 2021, 208
  • [8] Genetic contribution of suppressor of cytokine signalling polymorphisms to the susceptibility to infection after traumatic injury
    Zhang, A.
    Gu, W.
    Lu, H.
    Zeng, L.
    Zhang, L.
    Du, D.
    Hao, J.
    Wen, D.
    Wang, X.
    Jiang, J.
    [J]. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2018, 194 (01): : 93 - 102
  • [9] Neuroglobin Genetic Polymorphisms and Their Relationship to Functional Outcomes after Traumatic Brain Injury
    Chuang, Pei-Ying
    Conley, Yvette P.
    Poloyac, Samuel M.
    Okonkwo, David O.
    Ren, Dianxu
    Sherwood, Paula R.
    Hravnak, Marilyn
    Alexander, Sheila A.
    [J]. JOURNAL OF NEUROTRAUMA, 2010, 27 (06) : 999 - 1006
  • [10] NEUROGLOBIN GENETIC POLYMORPHISMS AND THEIR RELATIONSHIP TO FUNCTIONAL OUTCOME FOLLOWING TRAUMATIC BRAIN INJURY
    Chuang, Pei-Ying
    Conley, Yvette
    Alexander, Sheila
    Ren, Dianxu
    Hravnak, Marilyn
    Poloyac, Samuel
    [J]. CRITICAL CARE MEDICINE, 2008, 36 (12) : A10 - A10
12345